User profiles for T. HORIUCHI

堀内敏彦

Other name: Toshihiko Horiuchi
防災科学技術研究所
Verified email at bosai.go.jp
Cited by 1210

Transmembrane TNF-α: structure, function and interaction with anti-TNF agents

T Horiuchi, H Mitoma, S Harashima… - …, 2010 - academic.oup.com
T cells, without detectable changes in peripheral blood T lymphocyte phenotype or
markers of apoptosis [104]. Moreover, transmembrane TNF-α, in the absence of soluble TNF-α, …

[HTML][HTML] Immunogenicity of biologics in chronic inflammatory diseases: a systematic review

…, J Al-Saleh, L Barile-Fabris, T Horiuchi, T Takeuchi… - BioDrugs, 2017 - Springer
… These biologic agents include a T cell activation inhibitor/co-stimulation modulator, tumor
necrosis factor inhibitor (TNFi) monoclonal antibodies (mAbs) and receptor fusion protein, an …

Molecular mechanisms of action of anti-TNF-α agents–Comparison among therapeutic TNF-α antagonists

H Mitoma, T Horiuchi, H Tsukamoto, N Ueda - Cytokine, 2018 - Elsevier
… in activated T lymphocytes. Infliximab, adalimumab and certolizumab pegol, but not
etanercept, were able to induce apoptosis of T lymphocytes in IBD only when mucosal CD4+ T

Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway

…, S Sato, H Sanjo, K Hoshino, T Horiuchi… - Nature …, 2002 - nature.com
The imidazoquinoline compounds imiquimod and R-848 are low-molecular-weight immune
response modifiers that can induce the synthesis of interferon-α and other cytokines in a …

Solar neutrino data covering solar cycle 22

…, Y Oyama, M Koshiba, K Nishijima, T Horiuchi… - Physical Review Letters, 1996 - APS
Results from 1036 days of solar neutrino data accumulated in the upgraded Kamiokande
detector (Kamiokande III) are presented. The B 8 solar neutrino flux observed in Kamiokande III …

High efficiency of dye-sensitized solar cells based on metal-free indoline dyes

T Horiuchi, H Miura, K Sumioka… - Journal of the American …, 2004 - ACS Publications
We now report metal-free organic dyes having a new type of indoline structure, which
exhibits high efficiencies in dye-sensitized solar cells. The solar energy to current conversion …

Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins

O Takeuchi, S Sato, T Horiuchi, K Hoshino… - The Journal of …, 2002 - journals.aai.org
The Toll-like receptor (TLR) family acts as pattern recognition receptors for pathogen-specific
molecular patterns (PAMPs). TLR2 is essential for the signaling of a variety of PAMPs, …

Production of human α-interferon in silkworm using a baculovirus vector

S Maeda, T Kawai, M Obinata, H Fujiwara, T Horiuchi… - Nature, 1985 - nature.com
Microorganisms are generally used for mass production of foreign gene products, but
multicellular organisms such as plants have been proposed as an economical alternative. The …

Escherichia coli K-12: a cooperatively developed annotation snapshot—2005

…, T Horiuchi, IM Keseler, T Kosuge… - Nucleic acids …, 2006 - academic.oup.com
The goal of this group project has been to coordinate and bring up-to-date information on all
genes of Escherichia coli K-12. Annotation of the genome of an organism entails …

Real‐time hybrid experimental system with actuator delay compensation and its application to a piping system with energy absorber

T Horiuchi, M Inoue, T Konno… - … Engineering & Structural …, 1999 - Wiley Online Library
… N and the actual delay t is at most 0)5 ms. … Inoue and T. Horiuchi, &Seismic experiment of
FRP columns in a thyristor valve by real-time vibration testing method', ¹rans. Japan Soc. Mech. …