Background Osteoarthritis (OA) is a multifactorial disease characterized by destruction of the
articular cartilage due to environmental, mechanical and genetic components. The genetics …

The human amniotic membrane (HAM) contains two cell types from different embryological
origins. Human amnion epithelial cells (hAECs) are derived from the embryonic ectoderm, …

The human amniotic membrane (HAM) is a highly abundant and readily available tissue.
This amniotic tissue has considerable advantageous characteristics to be considered as an …

… were extracted by washing the bone marrow with Dulbecco’s modified Eagle’s medium (DMEM;
Lonza, Spain) and cultured in the same medium as described by Hermida-Gomez et al. (…

The human amniotic membrane (HAM) is an abundant and readily obtained tissue that may
be an important source of scaffold for transplanted chondrocytes in cartilage regeneration in …

… T. Hermida-Gómez holds a contract from Fondo de Investigación Sanitaria (2008). E.
Muiños-Lopez is supported by Fundacion Española de Reumatologia. … Muneta T …

Introduction: The human amniotic membrane is a highly abundant and readily available
tissue that may be useful for regenerative medicine and cell therapy. Aim: To compare two …

Background. The interests in mesenchymal stem cells (MSCs) and their application in cell
therapy have resulted in a better understanding of the basic biology of these cells. Recently …

The establishment of cartilage regenerative medicine is an important clinical issue, but the
search for cell sources able to restore cartilage integrity proves to be challenging. Human …

Objective To evaluate the influence of the mitochondrial DNA (mtDNA) haplogroups in the
risk of incident knee osteoarthritis (OA) and to explain the functional consequences of this …