Objective To develop and validate an international set of classification criteria for primary
Sjögren's syndrome (SS) using guidelines from the American College of Rheumatology (ACR) …

Labial salivary gland (LSG) biopsy is used in the classification of primary Sjögren's syndrome
(PSS) and in patient stratification in clinical trials. It may also function as a biomarker. The …

Autoimmune muscle diseases (myositis) comprise a group of complex phenotypes
influenced by genetic and environmental factors. To identify genetic risk factors in patients of …

… Radstake has received consulting fees from Janssen (less than $10,000) and owns stock
or stock options in AbbVie. No other disclosures relevant to this article were reported. …

The tyrosine phosphatase PTPN22 allele 1858T has been associated with rheumatoid
arthritis (RA) and other autoimmune diseases. RA is the most frequent of those multifactorial …

Introduction The acute gout flare results from a localised self-limiting innate immune response
to monosodium urate (MSU) crystals deposited in joints in hyperuricaemic individuals. …

Splenic macrophages play a key role in immune thrombocytopenia (ITP) pathogenesis by
clearing opsonized platelets. Fcγ receptors (FcγR) participate in this phenomenon, but their …

Growing evidence supports the idea that aberrancies in epigenetic processes contribute to
the onset and progression of human immune-mediated inflammatory diseases, such as …

… J Bayry is an international scientific committee member and TR Radstake is an organizing
committee member of the Seventh European Workshop on Immune-Mediated Inflammatory …

In the early 1990s, Janeway discussed the theory that an immune response could not occur
unless antigen-presenting cells (APCs) were first activated, which he called “the …