Development and validation of the sociocultural attitudes towards appearance questionnaire-4 (SATAQ-4).

…, H Dittmar, E Clark, Z Adams, S Macwana… - Psychological …, 2015 - psycnet.apa.org
The Sociocultural Attitudes Towards Appearance Questionnaire-3 (SATAQ-3) and its earlier
versions are measures designed to assess societal and interpersonal aspects of …

Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus

…, TB Niewold, DL Kamen, SR Macwana… - Annals of the …, 2011 - ard.bmj.com
Objectives Vitamin D deficiency is widespread and has been associated with many chronic
diseases, including autoimmune disorders. A study was undertaken to explore the impact of …

Genetic associations of LYN with systemic lupus erythematosus

…, AM Delgado-Vega, XK Howard, SR Macwana… - Genes & …, 2009 - nature.com
We targeted LYN, a src-tyosine kinase involved in B-cell activation, in case–control association
studies using populations of European-American, African-American and Korean subjects…

[PDF][PDF] Two functional lupus-associated BLK promoter variants control cell-type-and developmental-stage-specific transcription

…, C Sun, GB Wiley, N Dominguez, SR Macwana… - The American Journal of …, 2014 - cell.com
Efforts to identify lupus-associated causal variants in the FAM167A/BLK locus on 8p21 are
hampered by highly associated noncausal variants. In this report, we used a trans-population …

[HTML][HTML] Adults with systemic lupus exhibit distinct molecular phenotypes in a cross-sectional study

…, T Gross, W DeJager, SR Macwana… - …, 2020 - thelancet.com
Background The clinical and pathologic diversity of systemic lupus erythematosus (SLE)
hinders diagnosis, management, and treatment development. This study addresses …

Herpes zoster vaccination in SLE: a pilot study of immunogenicity

…, A Cogman, JT Merrill, S Macwana… - The Journal of …, 2013 - jrheum.org
Objective. Patients with systemic lupus erythematosus (SLE) are at increased risk of herpes
zoster (HZ). Although a vaccine for HZ has been approved by the US Food and Drug …

[HTML][HTML] Site-1 protease deficiency causes human skeletal dysplasia due to defective inter-organelle protein trafficking

…, L Pollard, S Cathey, T Yago, G Wiley, S Macwana… - JCI insight, 2018 - ncbi.nlm.nih.gov
Site-1 protease (S1P), encoded by MBTPS1, is a serine protease in the Golgi. S1P regulates
lipogenesis, endoplasmic reticulum (ER) function, and lysosome biogenesis in mice and in …

Autoantibody-positive healthy individuals with lower lupus risk display a unique immune endotype

S Slight-Webb, M Smith, A Bylinska, S Macwana… - Journal of Allergy and …, 2020 - Elsevier
Background Autoimmune diseases comprise a spectrum of illnesses and are on the rise
worldwide. Although antinuclear antibodies (ANAs) are detected in many autoimmune diseases…

[HTML][HTML] Mycophenolate mofetil reduces STAT3 phosphorylation in systemic lupus erythematosus patients

…, EF Chakravarty, H Chen, R Lu, S Macwana… - JCI insight, 2019 - ncbi.nlm.nih.gov
Systemic lupus erythematosus (SLE) is a highly variable autoimmune disease that can
involve severe organ-threatening symptoms, such as lupus nephritis. Certain drugs, such as …

[HTML][HTML] Serologic markers of Epstein-Barr virus reactivation are associated with increased disease activity, inflammation, and interferon pathway activation in patients …

…, CA Wagner, H Chen, W DeJager, SR Macwana… - Journal of Translational …, 2021 - Elsevier
SLE is a clinically heterogeneous disease characterized by an unpredictable relapsing-remitting
disease course. Although the etiology and mechanisms of SLE flares remain elusive, …