Intestinal microfold (M) cells possess a high transcytosis capacity and are able to transport a
broad range of materials including particulate antigens, soluble macromolecules, and …

Following severe adverse reactions to the AstraZeneca ChAdOx1-S-nCoV-19 vaccine 1 , 2 ,
European health authorities recommended that patients under the age of 55 years who …

Mucosal surfaces are the major entrance for infectious pathogens and therefore mucosal
immune responses serve as a first line of defence. Most current immunization procedures are …

Background & Aims Little is known about the association between pharmacokinetic features
of adalimumab and mucosal healing in patients with inflammatory bowel disease (IBD). …

Background Data on the value of therapeutic drug monitoring of infliximab (IFX) to predict
mucosal healing (MH) in inflammatory bowel diseases (IBD) are scarce. Methods All …

Background To address the unmet medical need for an effective prophylactic vaccine
against Ebola virus we assessed the safety and immunogenicity of three different two-dose …

Understanding the immune responses elicited by SARS-CoV-2 infection is critical in terms
of protection against reinfection and, thus, for public health policy and vaccine development …

TLR ligands are critical activators of innate immunity and are being developed as vaccine
adjuvants. However, their usefulness in conjunction with NOD-like receptor agonists remains …

Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/ml; in plasma
diluted 1:10) of IFN-α and/or IFN-ω are found in about 10% of patients with critical COVID-19 …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR)
doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing …