Background and objectives: As a major component of uremic syndrome, cardiovascular
disease is largely responsible for the high mortality observed in chronic kidney disease (CKD). …

Background. Uraemic toxins are considered to be emerging mortality risk factors in chronic
kidney disease (CKD) patients. p-Cresol (a prototype protein-bound uraemic retention solute) …

Chronic inflammation associated with chronic kidney disease predicts all-cause and
cardiovascular mortality in hemodialysis patients. Here we sought to evaluate the association …

Background and objectives: Vitamin K-dependent matrix Gla protein (MGP) acts as a calcification
inhibitor in vitro and in vivo. The present study was performed to (1) determine plasma …

Background Increased arterial stiffness and vascular calcification have been recognized as
important predictors of cardiovascular mortality in patients with chronic kidney disease. …

Background and objectives: Cardiovascular disease is the main cause of mortality in chronic
kidney disease (CKD) patients. Vitamin D might have beneficial effects on vascular health. …

Since beta-2 microglobulin (B2M) is a surrogate marker for middle molecular weight uremic
toxins and the major protein component in dialysis-related amyloidosis, it has been …

Results Monocytes incubated with SDMA showed increased IL-6 and TNF-α expression and
a rise in active NF-κB. N-acetylcysteine abrogated both these effects. No significant effects …

The uremic syndrome is attributed to the progressive retention of a large number of compounds
which, under normal conditions, are excreted by healthy kidneys. The compounds are …

Aims Acute kidney injury (AKI) is associated with a high hospitalization rate, accelerated
long‐term decline in kidney function and a high mortality rate. Adverse drug reactions (ADRs) …