Background: Rheumatoid factor (RF) and autoantibodies against cyclic citrullinated peptide (CCP)
are markers that might help physicians diagnose rheumatoid arthritis. Purpose: To …

Multicentric Castleman disease (MCD) is an atypical lymphoproliferative disorder characterized
by systemic lymphadenopathy and constitutional inflammatory symptoms. Dysregulated …

Objectives: To assess whether smoking is a risk factor for developing rheumatoid arthritis (RA).
Design: Meta-analysis. Method: Data sources were observational studies that examined …

Objective To elucidate the role of microRNA (miRNA) in the pathogenesis of rheumatoid
arthritis (RA), we analyzed synoviocytes from RA patients for their miRNA expression. Methods …

Serum 1,3-β-d-glucan (BG) assay may be helpful as a marker for the diagnosis of Pneumocystis
jiroveci pneumonia (PJP) and invasive fungal infection (IFI). We conducted a systematic …

Nakajo-Nishimura syndrome (NNS) is a disorder that segregates in an autosomal recessive
fashion. Symptoms include periodic fever, skin rash, partial lipomuscular atrophy, and joint …

Objective To examine cancer incidence in patients with systemic sclerosis (SSc) through a
meta‐analysis of population‐based cohort studies. Methods Five different databases (Medline…

The aim of this study was to investigate the types and prevalence of disease-specific antinuclear
antibodies (ANAs) and their relationship to rheumatic diseases in the general Japanese …

There is no doubt that oxidative stress occurs in patients with rheumatoid arthritis (RA) and
play an important role in both inflammation and destruction of RA joints. Thioredoxin (TRX) is …

STUDIES on transgenic mice expressing immunoglobulins against self-antigens 1–6 have
shown that self-tolerance is maintained by active elimination (clonal deletion) 1–3,7 , …