A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis
…, Y Zhang, Q Lv, Q Wei, HQ Low, YM Guo, S Cao… - Nature …, 2012 - nature.com
To identify susceptibility loci for ankylosing spondylitis, we performed a two-stage genome-wide
association study in Han Chinese. In the discovery stage, we analyzed 1,356,350 …
association study in Han Chinese. In the discovery stage, we analyzed 1,356,350 …
[HTML][HTML] MiR-27a targets sFRP1 in hFOB cells to regulate proliferation, apoptosis and differentiation
D Guo, Q Li, Q Lv, Q Wei, S Cao, J Gu - PloS one, 2014 - journals.plos.org
MicroRNAs (miRNAs) play a key role in the regulation of almost all the physiological and
pathological processes, including bone metabolism. Recent studies have suggested that miR-…
pathological processes, including bone metabolism. Recent studies have suggested that miR-…
The relationship between disease activity measured by the BASDAI and psychological status, stressful life events, and sleep quality in ankylosing spondylitis
…, Y Zhang, Y Li, L Shen, A Huang, Z Liao, S Cao… - Clinical …, 2015 - Springer
Bath Ankylosing Spondylitis Disease Activity Index (BASDAI) is a standard instrument regularly
used to assess disease activity of patients with ankylosing spondylitis (AS). However, the …
used to assess disease activity of patients with ankylosing spondylitis (AS). However, the …
Prevalence of psychological disorders, sleep disturbance and stressful life events and their relationships with disease parameters in Chinese patients with ankylosing …
…, S Hu, Y Li, L Shen, A Huang, Q Wei, S Cao… - Clinical …, 2018 - Springer
Our aim was to investigate the prevalence of psychological disorders, sleep disturbance,
and stressful life events in Chinese patients with ankylosing spondylitis (AS) and healthy …
and stressful life events in Chinese patients with ankylosing spondylitis (AS) and healthy …
[HTML][HTML] Serum metabolomics signatures associated with ankylosing spondylitis and TNF inhibitor therapy
J Ou, M Xiao, Y Huang, L Tu, Z Chen, S Cao… - Frontiers in …, 2021 - frontiersin.org
Ankylosing spondylitis (AS) is a type of spondyloarthropathies, the diagnosis of which is often
delayed. The lack of early diagnosis tools often delays the institution of appropriate therapy…
delayed. The lack of early diagnosis tools often delays the institution of appropriate therapy…
[HTML][HTML] TNF-α inhibitor therapy can improve the immune imbalance of CD4+ T cells and negative regulatory cells but not CD8+ T cells in ankylosing spondylitis
…, Y Jiang, J Qi, M Xiao, L Fang, Y Xie, S Cao… - Arthritis Research & …, 2020 - Springer
Background Studies into ankylosing spondylitis (AS) and its relationship with immune
imbalance are controversial, and the correlation between the efficacy of TNF-α inhibitor and …
imbalance are controversial, and the correlation between the efficacy of TNF-α inhibitor and …
Identification of the urine and serum metabolomics signature of gout
…, L Tu, Y Jiang, X Zhang, J Qi, M Qiu, S Cao… - …, 2020 - academic.oup.com
Objective Gout is the most common inflammatory arthritis and the worldwide incidence is
increasing. By revealing the metabolic alterations in serum and urine of gout patients, the first …
increasing. By revealing the metabolic alterations in serum and urine of gout patients, the first …
Adalimumab significantly reduces inflammation and serum DKK‐1 level but increases fatty deposition in lumbar spine in active ankylosing spondylitis
Z Hu, M Xu, Q Li, Z Lin, Z Liao, S Cao… - International Journal …, 2012 - Wiley Online Library
Aim To investigate whether adalimumab is effective for active ankylosing spondylitis ( AS )
patients and whether it has an impact on the formation of fatty deposition lesions ( FDL ) and …
patients and whether it has an impact on the formation of fatty deposition lesions ( FDL ) and …
[HTML][HTML] Disorders of MicroRNAs in peripheral blood mononuclear cells: as novel biomarkers of ankylosing spondylitis and provocative therapeutic targets
…, P Zhang, Y Jiang, X Wang, Q Wei, S Cao… - BioMed research …, 2015 - hindawi.com
Background. MicroRNAs can potentially regulate every aspect of cellular activity. In this
study, we investigated whether AS pathogenesis involves microRNAs disorders. Result. The …
study, we investigated whether AS pathogenesis involves microRNAs disorders. Result. The …
Comorbidities and factors influencing frequent gout attacks in patients with gout: a cross-sectional study
…, F Liu, Y Zhang, M Yang, J Wu, M Xiao, S Cao… - Clinical …, 2021 - Springer
Objectives The objective was to identify the comorbidities of gout, to compare gender
difference and independent factors of frequent gout attacks (> 20 times). Method Demographic, …
difference and independent factors of frequent gout attacks (> 20 times). Method Demographic, …