User profiles for Shin-Seok Lee

Shin-Seok Lee

Verified email at chonnam.ac.kr
Cited by 4419

Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a …

…, JY Choe, YM Kang, SR Kwon, SH Lee, SS Lee… - The Lancet, 2017 - thelancet.com
Background Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid
arthritis. The Oral Rheumatoid Arthritis triaL (ORAL) Strategy aimed to assess the comparative …

Three multicenter, randomized, double‐blind, placebo‐controlled studies evaluating the efficacy and safety of ustekinumab in axial spondyloarthritis

…, CK Lee, SH Lee, SH Lee, SS Lee… - Arthritis & …, 2019 - Wiley Online Library
Objective To evaluate the efficacy and safety of ustekinumab in 3 randomized, placebo‐controlled
studies in patients with axial spondyloarthritis (SpA). Studies 1 and 2 included patients …

Impaired differentiation and cytotoxicity of natural killer cells in systemic lupus erythematosus

…, SJ Kee, YN Cho, EH Lee, HY Lee… - … : Official Journal of …, 2009 - Wiley Online Library
Objective To determine the cytotoxicity of natural killer (NK) cells and the level of differentiation
of hematopoietic stem cells (HSCs) into NK cells in systemic lupus erythematosus (SLE). …

High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry

…, P Motghare, K Bhattarai, A Adler, SY Bang, HS Lee… - Nature …, 2016 - nature.com
Systemic lupus erythematosus (SLE) has a strong but incompletely understood genetic
architecture. We conducted an association study with replication in 4,478 SLE cases and 12,656 …

Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus

…, JM Shin, K Li, Y Kawaguchi, YK Lee… - Annals of the …, 2021 - ard.bmj.com
Objective Systemic lupus erythematosus (SLE), an autoimmune disorder, has been associated
with nearly 100 susceptibility loci. Nevertheless, these loci only partially explain SLE …

Mucosal-associated invariant T cell deficiency in systemic lupus erythematosus

…, MJ Kim, HJ Jung, KJ Park, SJ Lee, SS Lee… - The Journal of …, 2014 - journals.aai.org
Mucosal-associated invariant T (MAIT) cells contribute to protection against certain microorganism
infections and play an important role in mucosal immunity. However, the role of MAIT …

Elevated vascular endothelial growth factor in systemic sclerosis.

…, DJ Min, ML Cho, SY Min, SJ Kim, SS Lee… - The Journal of …, 2003 - jrheum.org
OBJECTIVE: To determine the serum levels of vascular endothelial growth factor (VEGF) in
patients with systemic sclerosis (SSc) and to search for relationships between its serum …

High-density genotyping of immune loci in Koreans and Europeans identifies eight new rheumatoid arthritis risk loci

…, SK Kim, CH Suh, SC Shim, SS Lee, J Lee… - Annals of the …, 2015 - ard.bmj.com
Objective A highly polygenic aetiology and high degree of allele-sharing between ancestries
have been well elucidated in genetic studies of rheumatoid arthritis. Recently, the high-…

[PDF][PDF] Fenebrutinib versus placebo or Adalimumab in rheumatoid arthritis: A randomized, Double‐Blind, phase II trial

…, CK Lee, CH Suh, EY Lee, SH Lee… - Arthritis & …, 2020 - Wiley Online Library
Lee owns stock or stock options in Genentech/Roche and Eli Lilly. Ms Rae, Mr. Toth, and
Drs. … Nigrovic PA, Lee DM. Mast cells in inflammatory arthritis. Arthritis Res Ther 2005;7:1–11. …

Circulating mucosal-associated invariant T cell levels and their cytokine levels in healthy adults

OJ Lee, YN Cho, SJ Kee, MJ Kim, HM Jin, SJ Lee… - Experimental …, 2014 - Elsevier
Mucosal-associated invariant T (MAIT) cells have been reported to play an antimicrobial role
in infectious diseases. However, little is known about age- and gender-related changes in …