CD4+ T lymphocytes provide contact-dependent stimuli to B cells that are critical for the
generation of specific antibody responses in a process termed T helper function. The surface …

CD40 is a receptor on the surface of B lymphocytes, the activation of which leads to B cell
survival, growth, and differentiation. A yeast two-hybrid screen identified a gene, CRAF1, …

Edward Jenner and his contemporaries believed that his variolae vaccinae originated in
horses and molecular analyses show that modern vaccinia virus (VACV) strains share common …

Backgound The CD40 ligand (CD40L) is a member of the tumor necrosis factor (TNF) family
of proteins and is transiently expressed on the surface of activated T cells. The binding of …

The T-BAM/CD40-L molecule on CD4+ T cells interacts with B cell CD40 molecules to
deliver contact-dependent signals that drive B cell activation and Ig secretion. Cell surface T-BAM/…

CD40 was originally described as a functionally significant B cell surface molecule. However,
CD40 is also expressed on monocytes, dendritic cells, epithelial cells, and basophils. We …

The CD4 molecule is a relatively non-polymorphic 55 kDa glycoprotein expressed on a
subset of T lymphocytes. A common African allele of CD4 has been identified by non-reactivity …

In lymphoid follicles, CD4+ T lymphocytes provide contact-dependent stimuli to B cells that
are critical for the generation of specific antibody responses in a process termed Th function. …

Objective. To determine the effects of bedtime very low dose (VLD) cyclobenzaprine (CBP)
on symptoms and sleep physiology of patients with fibromyalgia (FM), unrefreshing sleep, …

CD8+ CD28− human T suppressor cells (Ts) act on APC, inhibiting their ability to elicit Th
activation and proliferation. This effect is due to inhibition of the CD40 pathway which normally …