User profiles for Seiji Minota

Seiji Minota

Jichi Medical University, Tochigi, Japan
Verified email at jichi.ac.jp
Cited by 7722

Increased levels of interleukin 33 in sera and synovial fluid from patients with active rheumatoid arthritis

…, M Iwamoto, T Yoshio, SI Tominaga, S Minota - The Journal of …, 2010 - jrheum.org
Objective. To determine levels of interleukin 33 (IL-33) in serum and synovial fluid (SF) and
their clinical associations in patients with rheumatoid arthritis (RA). To evaluate the ability of …

Identification of human ST2 protein in the sera of patients with autoimmune diseases

K Kuroiwa, T Arai, H Okazaki, S Minota… - … and biophysical research …, 2001 - Elsevier
Soluble human ST2 protein (IL1RL1-a) in the sera of patients with various autoimmune
diseases was identified by a newly developed procedure using specific monoclonal antibodies. …

Potent induction of IFN-α and chemokines by autoantibodies in the cerebrospinal fluid of patients with neuropsychiatric lupus

DM Santer, T Yoshio, S Minota, T Möller… - The Journal of …, 2009 - journals.aai.org
Neuropsychiatric disease in systemic lupus erythematosus (NPSLE) is a poorly understood,
but potentially fatal, disease manifestation. A pathogenetic role for autoantibodies is …

CD52 is a novel costimulatory molecule for induction of CD4+ regulatory T cells

…, K Kojima, Y Uemura, Y Aoki, S Kaga, S Minota… - Clinical …, 2006 - Elsevier
We previously reported that 4C8 monoclonal antibody (mAb) provides a costimulatory signal
to human CD4 + T cells and consequently induces regulatory T (Treg) cells, which are hypo-…

Pneumocystis jiroveci pneumonia in patients with rheumatoid arthritis treated with infliximab: A retrospective review and case–control study of 21 patients

…, K Hiramatsu, M Iwamoto, S Minota… - Arthritis Care & …, 2009 - Wiley Online Library
Objective To establish proper management of Pneumocystis jiroveci pneumonia (PCP) in
rheumatoid arthritis (RA) patients treated with infliximab. PCP has been observed in 0.4% of …

Tocilizumab in systemic juvenile idiopathic arthritis in a real-world clinical setting: results from 1 year of postmarketing surveillance follow-up of 417 patients in Japan

…, M Tomobe, K Tanaka, S Minota - Annals of the …, 2016 - ard.bmj.com
Objectives To evaluate the safety and effectiveness of tocilizumab (TCZ) in patients with
systemic juvenile idiopathic arthritis (sJIA) in real-world clinical settings in Japan. Methods …

Effects of FTY720 in MRL-lpr/lpr mice: therapeutic potential in systemic lupus erythematosus.

…, A Fujimura, E Kobayashi, S Kano, S Minota - The Journal of …, 2002 - jrheum.org
OBJECTIVE To examine the effects of a novel immunosuppressant, FTY720, on hematolymphoid
cells and the clinical course of MRL-lpr/lpr (MRL/lpr) mice genetically predisposed to …

Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis under treatment with tocilizumab

…, T Morio, N Sumitomo, K Daimaru, S Minota - The Journal of …, 2015 - jrheum.org
Objective. To identify macrophage activation syndrome (MAS) in patients with systemic
juvenile idiopathic arthritis (sJIA) undergoing tocilizumab (TCZ) treatment, and to confirm …

IgG anti–NR2 glutamate receptor autoantibodies from patients with systemic lupus erythematosus activate endothelial cells

…, H Okamoto, S Hirohata, S Minota - Arthritis & …, 2013 - Wiley Online Library
Objective To investigate the possibility that IgG anti–NR2 glutamate receptor antibodies (anti‐NR2)
derived from patients with systemic lupus erythematosus (SLE) cause an …

Apoptosis of rheumatoid synovial cells by statins through the blocking of protein geranylgeranylation: a potential therapeutic approach to rheumatoid arthritis

…, K Yudoh, H Matsuno, S Minota - … : Official Journal of …, 2006 - Wiley Online Library
Objective To determine whether statins induce apoptosis in rheumatoid arthritis (RA)
synoviocytes. Methods The effects of lipophilic and hydrophilic statins (fluvastatin and pravastatin, …