[HTML][HTML] Baricitinib in patients with refractory rheumatoid arthritis

…, M Krogulec, L Xie, SD Beattie… - … England Journal of …, 2016 - Mass Medical Soc
Background In phase 2 studies, baricitinib, an oral Janus kinase 1 and 2 inhibitor, reduced
disease activity in patients with rheumatoid arthritis who had not previously received …

[HTML][HTML] Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate

…, E Drescher, DE Schlichting, SD Beattie… - Annals of the …, 2015 - ard.bmj.com
Objectives To investigate baricitinib (LY3009104, formerly INCB028050), a novel, oral
inhibitor of JAK1/JAK2 in patients with moderate to severe rheumatoid arthritis (RA) despite …

Natural history of cardiovascular disease in patients with diabetes: role of hyperglycemia

Z Milicevic, I Raz, SD Beattie, BN Campaigne… - Diabetes …, 2008 - Am Diabetes Assoc
Atherosclerotic vascular disease is more common in diabetic than in nondiabetic individuals.
Diabetic macrovascular disease also has a more severe course with greater prevalence of …

[HTML][HTML] Safety and efficacy of baricitinib through 128 weeks in an open-label, longterm extension study in patients with rheumatoid arthritis

…, DE Schlichting, I de la Torre, SD Beattie… - The Journal of …, 2018 - jrheum.org
Objective. To assess the safety and efficacy of baricitinib in patients with rheumatoid arthritis
(RA) up to 128 weeks in a phase IIb study (NCT01185353). Methods. After a 24-week …

A two-stage Bayesian model selection strategy for supersaturated designs

SD Beattie, DKH Fong, DKJ Lin - Technometrics, 2002 - Taylor & Francis
In early stages of experimentation, one often has many candidate factors of which only few
have significant influence on the response. Supersaturated designs can offer important …

Effects of baricitinib on lipid, apolipoprotein, and lipoprotein particle profiles in a phase IIb study of patients with active rheumatoid arthritis

…, VL Crotzer, E Nantz, SD Beattie… - Arthritis & …, 2017 - Wiley Online Library
Objective To assess the effects of baricitinib on lipid profiles in patients with moderate‐to‐severe
rheumatoid arthritis. Methods Treatment with once‐daily doses of baricitinib (1, 2, 4, or …

Recruitment to a clinical trial improves glycemic control in patients with diabetes

EAM Gale, SD Beattie, J Hu, V Koivisto… - Diabetes care, 2007 - Am Diabetes Assoc
OBJECTIVE—We assessed the effect upon A1C of recruitment to a clinical trial in patients
with diabetes who had been screened and interviewed to determine eligibility but whose …

Hyperglycemia and its effect after acute myocardial infarction on cardiovascular outcomes in patients with type 2 diabetes mellitus (HEART2D): study design

…, J Skrha, MH Tan, JW Wyatt, SD Beattie… - Journal of Diabetes and …, 2005 - Elsevier
OBJECTIVE: Cardiovascular (CV) disease is the major cause of death in patients with
diabetes. Up to 40% of patients with Type 2 diabetes mellitus (T2DM) who survive an initial …

Rotated factorial designs for computer experiments

SD Beattie, DKJ Lin - 中國統計學報, 2004 - airitilibrary.com
Computer models can describe complicated phenomena encountered in science and
engineering fields. To use these models for scientific investigation, however, their generally long …

Therapy after single oral agent failure: adding a second oral agent or an insulin mixture?

JK Malone, SD Beattie, BN Campaigne… - Diabetes research and …, 2003 - Elsevier
Aim: to compare the glycemic response to an insulin lispro mixture (25% insulin lispro and
75% NPL) twice daily plus metformin (Mix25+M) with glibenclamide plus metformin (G+M), in …