[HTML][HTML] Baricitinib in patients with refractory rheumatoid arthritis
…, M Krogulec, L Xie, SD Beattie… - … England Journal of …, 2016 - Mass Medical Soc
Background In phase 2 studies, baricitinib, an oral Janus kinase 1 and 2 inhibitor, reduced
disease activity in patients with rheumatoid arthritis who had not previously received …
disease activity in patients with rheumatoid arthritis who had not previously received …
[HTML][HTML] Safety and efficacy of baricitinib at 24 weeks in patients with rheumatoid arthritis who have had an inadequate response to methotrexate
…, E Drescher, DE Schlichting, SD Beattie… - Annals of the …, 2015 - ard.bmj.com
Objectives To investigate baricitinib (LY3009104, formerly INCB028050), a novel, oral
inhibitor of JAK1/JAK2 in patients with moderate to severe rheumatoid arthritis (RA) despite …
inhibitor of JAK1/JAK2 in patients with moderate to severe rheumatoid arthritis (RA) despite …
Natural history of cardiovascular disease in patients with diabetes: role of hyperglycemia
Z Milicevic, I Raz, SD Beattie, BN Campaigne… - Diabetes …, 2008 - Am Diabetes Assoc
Atherosclerotic vascular disease is more common in diabetic than in nondiabetic individuals.
Diabetic macrovascular disease also has a more severe course with greater prevalence of …
Diabetic macrovascular disease also has a more severe course with greater prevalence of …
[HTML][HTML] Safety and efficacy of baricitinib through 128 weeks in an open-label, longterm extension study in patients with rheumatoid arthritis
…, DE Schlichting, I de la Torre, SD Beattie… - The Journal of …, 2018 - jrheum.org
Objective. To assess the safety and efficacy of baricitinib in patients with rheumatoid arthritis
(RA) up to 128 weeks in a phase IIb study (NCT01185353). Methods. After a 24-week …
(RA) up to 128 weeks in a phase IIb study (NCT01185353). Methods. After a 24-week …
A two-stage Bayesian model selection strategy for supersaturated designs
In early stages of experimentation, one often has many candidate factors of which only few
have significant influence on the response. Supersaturated designs can offer important …
have significant influence on the response. Supersaturated designs can offer important …
Effects of baricitinib on lipid, apolipoprotein, and lipoprotein particle profiles in a phase IIb study of patients with active rheumatoid arthritis
…, VL Crotzer, E Nantz, SD Beattie… - Arthritis & …, 2017 - Wiley Online Library
Objective To assess the effects of baricitinib on lipid profiles in patients with moderate‐to‐severe
rheumatoid arthritis. Methods Treatment with once‐daily doses of baricitinib (1, 2, 4, or …
rheumatoid arthritis. Methods Treatment with once‐daily doses of baricitinib (1, 2, 4, or …
Recruitment to a clinical trial improves glycemic control in patients with diabetes
EAM Gale, SD Beattie, J Hu, V Koivisto… - Diabetes care, 2007 - Am Diabetes Assoc
OBJECTIVE—We assessed the effect upon A1C of recruitment to a clinical trial in patients
with diabetes who had been screened and interviewed to determine eligibility but whose …
with diabetes who had been screened and interviewed to determine eligibility but whose …
Hyperglycemia and its effect after acute myocardial infarction on cardiovascular outcomes in patients with type 2 diabetes mellitus (HEART2D): study design
…, J Skrha, MH Tan, JW Wyatt, SD Beattie… - Journal of Diabetes and …, 2005 - Elsevier
OBJECTIVE: Cardiovascular (CV) disease is the major cause of death in patients with
diabetes. Up to 40% of patients with Type 2 diabetes mellitus (T2DM) who survive an initial …
diabetes. Up to 40% of patients with Type 2 diabetes mellitus (T2DM) who survive an initial …
Rotated factorial designs for computer experiments
SD Beattie, DKJ Lin - 中國統計學報, 2004 - airitilibrary.com
Computer models can describe complicated phenomena encountered in science and
engineering fields. To use these models for scientific investigation, however, their generally long …
engineering fields. To use these models for scientific investigation, however, their generally long …
Therapy after single oral agent failure: adding a second oral agent or an insulin mixture?
JK Malone, SD Beattie, BN Campaigne… - Diabetes research and …, 2003 - Elsevier
Aim: to compare the glycemic response to an insulin lispro mixture (25% insulin lispro and
75% NPL) twice daily plus metformin (Mix25+M) with glibenclamide plus metformin (G+M), in …
75% NPL) twice daily plus metformin (Mix25+M) with glibenclamide plus metformin (G+M), in …