Background Informed consent is often cited as the “cornerstone” of research ethics. Its intent
is that participants enter research voluntarily, with an understanding of what their …

Objectives Few studies have explored the factors influencing user uptake of interventions
designed to enhance therapeutic drug monitoring (TDM). This study aimed to identify barriers …

By ensuring optimal dosing, therapeutic drug monitoring (TDM) improves outcomes in
critically ill patients by maximizing effectiveness while minimizing toxicity. Current methods for …

Allopurinol is the major drug used in the treatment of gout and hyperuricemia. Generally, the
drug is well tolerated, although a minority of people, about 2%, develop a hypersensitivity …

In this issue of The Journal, Singh, et al, from the University of Alabama, asked the key question
regarding outcomes for people with gout: what are the factors associated with achieving …

Aims Accurate documentation of medication administration time is imperative for many
therapeutic decisions, including dosing of intravenous antimicrobials. The objectives were to …

Aims Bayesian forecasting software can assist in guiding therapeutic drug monitoring (TDM)‐based
dose adjustments for amikacin to achieve therapeutic targets. This study aimed to …

Aims: This study investigated the safe use of metformin in patients with (1) type 2 diabetes
mellitus (T2DM) and heart failure on metformin, and (2) heart failure without T2DM and …

Aim Pharmacokinetics have historically been assessed using drug concentration data
obtained via blood draws and bench‐top analysis. The cumbersome nature of these typically …

The sources of bias in medication adherence research have not been comprehensively
explored. We aimed to identify biases expected to affect adherence research and to develop a …