Validación del FINDRISC (FINnish Diabetes Risk SCore) para la predicción del riesgo de diabetes tipo 2 en una población del sur de España. Estudio Pizarra

…, I Esteva, MSR de Adana, MC Almaraz, S Morcillo… - Medicina Clínica, 2012 - Elsevier
Fundamento y objetivo El objetivo de este estudio ha sido validar la capacidad del Finnish
Diabetes Risk Score (FINDRISC) de predecir el riesgo de diabetes mellitus tipo 2 (DM2) en …

Metabolically healthy but obese, a matter of time? Findings from the prospective Pizarra study

…, MSR de Adana, FJ Chaves, S Morcillo… - The Journal of …, 2013 - academic.oup.com
Background: Prospective longitudinal studies evaluating the relevance of “Metabolically
Healthy but Obese” (MHO) phenotype at risk for type 2 diabetes mellitus (T2D) and …

The role of vitamin D and VDR in carcinogenesis: Through epidemiology and basic sciences

BB Merchan, S Morcillo, G Martin-Nunez… - The Journal of steroid …, 2017 - Elsevier
In the last two decades vitamin D (VD) research has demonstrated new extraskeletal
actions of this pre-hormone, suggesting a protective role of this secosteroid in the onset, …

[HTML][HTML] Pro12Ala Polymorphism of the PPARG2 Gene Is Associated with Type 2 Diabetes Mellitus and Peripheral Insulin Sensitivity in a Population with a High Intake …

F Soriguer, S Morcillo, F Cardona, G Rojo-Martínez… - The Journal of …, 2006 - Elsevier
Activation of the PPAR gamma 2 gene (PPARG2) improves the action of insulin and its lipid
metabolism. We examined the association between Pro12Ala polymorphism of PPARG2, …

Vitamin D and incidence of diabetes: a prospective cohort study

I González-Molero, G Rojo-Martínez, S Morcillo… - Clinical nutrition, 2012 - Elsevier
BACKGROUND & AIMS: To investigate the relationship between levels of 25-hydroxyvitamin
D and the incidence of type 2 diabetes in a Spanish population. METHODS: We undertook …

Validation of the FINDRISC (FINnish Diabetes RIsk SCore) for prediction of the risk of type 2 diabetes in a population of southern Spain. Pizarra Study

…, MS Ruiz de Adana, MC Almaraz, S Morcillo… - Medicina …, 2011 - europepmc.org
Results The test showed good results both to detect undiagnosed DM2 (ROC-AUC 0.74) and
to predict incident DM2 (ROC-AUC 0.75). The best prediction of risk of incident DM2 was …

Genome-Wide Association Study of the Modified Stumvoll Insulin Sensitivity Index Identifies BCL2 and FAM19A2 as Novel Insulin Sensitivity Loci

…, J Luan, TM Frayling, MN Weedon, W Xie, S Morcillo… - Diabetes, 2016 - Am Diabetes Assoc
Genome-wide association studies (GWAS) have found few common variants that influence
fasting measures of insulin sensitivity. We hypothesized that a GWAS of an integrated …

Thyroid hormone levels predict the change in body weight: a prospective study

F Soriguer, S Valdes, S Morcillo, I Esteva… - European journal of …, 2011 - Wiley Online Library
Eur J Clin Invest 2011; 41 (11): 1202–1209 Abstract Background Different studies, mostly
cross‐sectional, have found an association between low levels of thyroid hormones, even …

Relación entre déficit de vitamina D y síndrome metabólico

I González-Molero, G Rojo, S Morcillo, V Pérez-Valero… - Medicina Clínica, 2014 - Elsevier
Fundamento y objetivo El déficit de vitamina D y el síndrome metabólico son 2 entidades
muy frecuentes en población española. Se ha sugerido que los pacientes con síndrome …

[HTML][HTML] Altered adipose tissue DNA methylation status in metabolic syndrome: relationships between global DNA methylation and specific methylation at adipogenic …

…, B Ramos-Molina, J Alcaide-Torres, S Morcillo… - Journal of clinical …, 2019 - mdpi.com
Metabolic syndrome (MetS) has been postulated to increase the risk for type 2 diabetes,
cardiovascular disease and cancer. Adipose tissue (AT) plays an important role in metabolic …