User profiles for SONIA HIX

Sonia Hix

Full Professor Faculdade de Medicina do ABC
Verified email at fmabc.br
Cited by 661

In Vivo Metabolism of tert-Butyl Hydroperoxide to Methyl Radicals. EPR Spin-Trapping and DNA Methylation Studies

S Hix, MB Kadiiska, RP Mason… - Chemical research in …, 2000 - ACS Publications
Metabolic activation of peroxides and hydroperoxides to free radicals is associated with the
tumor promoting activity of these compounds. tert-Butyl hydroperoxide (t-BOOH) metabolism …

[HTML][HTML] Sleepiness, inflammation and oxidative stress markers in middle-aged males with obstructive sleep apnea without metabolic syndrome: a cross-sectional …

DK Andaku, V D'Almeida, G Carneiro, S Hix, S Tufik… - Respiratory …, 2015 - Springer
Background The simultaneous occurrence of metabolic syndrome and excessive daytime
sleepiness are very common in obstructive sleep apnea (OSA) patients. Both conditions, if …

[HTML][HTML] Is age a risk factor for liver disease and metabolic alterations in ataxia Telangiectasia patients?

TL Paulino, MN Rafael, S Hix, DC Shigueoka… - Orphanet Journal of …, 2017 - Springer
Background Ataxia telangiectasia (AT) is a neurodegenerative disease that leads to mitochondrial
dysfunction and oxidative stress. Insulin resistance (IR), type 2 diabetes and the risk …

Sleep deprivation alters gene expression and antioxidant enzyme activity in mice splenocytes

…, MS Marques, VG Pereira, S Hix… - Scandinavian …, 2013 - Wiley Online Library
Cellular defence against the formation of reactive oxygen species (ROS) involves a number
of mechanisms in which antioxidant enzymes such as catalase ( CAT ) and superoxide …

Lipid profile among girls with systemic lupus erythematosus

…, TTO Abad, SGL Silva, EJB Khazaal, S Hix… - Rheumatology …, 2017 - Springer
The aim of the study was to describe biomarkers of lipid metabolism associated with
increased cardiovascular risk and their correlation with disease variables and markers of …

DNA methylation by tert-butyl hydroperoxide-iron (II)

S Hix, MDS Morais, O Augusto - Free Radical Biology and Medicine, 1995 - Elsevier
Reduction of tert-butyl hydroperoxide (TBHP) by iron (II) at pH 4.0 or pH 7.0 in the presence
of calf thymus DNA led to generation of high yields of methyl radicals and to DNA methylation…

Risk of atherosclerosis in patients with ataxia telangiectasia

…, BT Costa-Carvalho, R Da Silva, S Hix… - Annals of Nutrition and …, 2015 - karger.com
Background and Aims: Evaluate the nutritional status, plasma concentration of vitamin E
and markers of cardiovascular risk in ataxia telangiectasia (AT) patients. Methods: Cross-…

Homocysteine and cysteine levels in prepubertal children: association with waist circumference and lipid profile

…, FIS de Souza, AI Pendezza, FLA Fonseca, S Hix… - Nutrition, 2013 - Elsevier
OBJECTIVE: To evaluate homocysteine and total cysteine levels in prepubertal children
and to determine the association between these levels and obesity, increased waist …

Higher cardiovascular risk in common variable immunodeficiency and X-linked agammaglobulinaemia patients

DG Vieira, BT Costa-Carvalho, S Hix… - Annals of Nutrition and …, 2015 - karger.com
Introduction: Common variable immunodeficiency and X-linked agammaglobulinaemia are
primary immunodeficiencies classified as antibody deficiencies, and they both result in …

DNA methylation by tert-butyl hydroperoxide-iron (II): a role for the transition metal ion in the production of DNA base adducts

S Hix, O Augusto - Chemico-biological interactions, 1999 - Elsevier
Metabolic degradation of both endogenous and exogenous peroxides is associated with the
etiology of several diseases including cancer. Tert-butyl hydroperoxide (TBHP) has been …