Urinary biomarkers in lupus nephritis

Y Li, M Tucci, S Narain, EV Barnes, ES Sobel… - Autoimmunity …, 2006 - Elsevier
There has long been a need for biomarkers of disease activity in lupus nephritis (LN). Such
markers ideally would be capable of detecting early sub-clinical disease and could be used …

Effective use of autoantibody tests in the diagnosis of systemic autoimmune disease

R Lyons, S Narain, C Nichols, M Satoh… - Annals of the New …, 2005 - Wiley Online Library
Screening for disease‐specific autoantibodies may be useful in asymptomatic ANA‐positive
individuals as a means of evaluating the risk of developing a systemic autoimmune disease …

The longitudinal immune response to coronavirus disease 2019: chasing the cytokine storm

AS Chau, AG Weber, NI Maria, S Narain… - Arthritis & …, 2021 - Wiley Online Library
The clinical progression of the severe acute respiratory syndrome coronavirus 2 infection,
coronavirus 2019 (COVID‐19), to critical illness is associated with an exaggerated immune …

Type I interferon as a novel risk factor for endothelial progenitor cell depletion and endothelial dysfunction in systemic lupus erythematosus

…, FS Chan, H Zhuang, S Narain… - … : Official Journal of …, 2007 - Wiley Online Library
Objective The premature atherosclerosis seen in patients with systemic lupus erythematosus
(SLE) is not explained by traditional risk factors. SLE disease activity, such as renal …

Comparative survival analysis of immunomodulatory therapy for coronavirus disease 2019 cytokine storm

S Narain, DG Stefanov, AS Chau, AG Weber, G Marder… - Chest, 2021 - Elsevier
Background Cytokine storm is a marker of coronavirus disease 2019 (COVID-19) illness
severity and increased mortality. Immunomodulatory treatments have been repurposed to …

Diagnostic accuracy for lupus and other systemic autoimmune diseases in the community setting

S Narain, HB Richards, M Satoh… - Archives of internal …, 2004 - jamanetwork.com
Background Most individuals with autoimmune and other immune disorders undergo initial
evaluation in the community setting. Since misdiagnosis of systemic autoimmune diseases …

[HTML][HTML] Increased expression of FcγRI/CD64 on circulating monocytes parallels ongoing inflammation and nephritis in lupus

Y Li, PY Lee, ES Sobel, S Narain, M Satoh… - Arthritis research & …, 2009 - Springer
Introduction The high-affinity receptor for IgG Fcγ/CD64 is critical for the development of
lupus nephritis (LN). Cross-linking Fc receptor on recruited monocytes by IgG-containing …

Citrulline dependence of anti-cyclic citrullinated peptide antibodies in systemic lupus erythematosus as a marker of deforming/erosive arthritis

P Kakumanu, ES Sobel, S Narain, Y Li… - The Journal of …, 2009 - jrheum.org
Objective. Anti-cyclic citrullinated peptide (CCP) antibodies are a serological marker for
rheumatoid arthritis (RA); up to 10%–15% of patients with systemic lupus erythematosus (SLE) …

Clinical implication of autoantibodies in patients with systemic rheumatic diseases

…, DL Kimpel, Y Yamasaki, S Narain… - Expert review of …, 2007 - Taylor & Francis
Autoantibodies have been used extensively as a useful biomarker in systemic lupus
erythematosus and other autoimmune rheumatic diseases. Antinuclear antibodies by …

Generation of a core set of items to develop classification criteria for scleroderma renal crisis using consensus methodology

…, T Medsger, P Merkel, S Narain… - Arthritis & …, 2019 - Wiley Online Library
Objective To generate a core set of items to develop classification criteria for scleroderma
renal crisis ( SRC ) using consensus methodology. Methods An international, multidisciplinary …