Multipopulation analysis of polymorphisms in five mononucleotide repeats used to determine the microsatellite instability status of human tumors

O Buhard, F Cattaneo, YF Wong, SF Yim… - Journal of clinical …, 2006 - ascopubs.org
Purpose Human gastrointestinal tumors with inactivated DNA mismatch repair system (microsatellite
instability [MSI] tumors) have distinct molecular and clinicopathologic profiles, and …

Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women

…, NY Huen, KWY Wong, KWK Lo, SF Yim… - … journal of cancer, 2009 - Wiley Online Library
The objective of this study, a parallel study to global gene expression profiling, was to
identify dysregulated microRNAs (miRNAs) associated with endometrioid endometrial …

Paclitaxel induces immunogenic cell death in ovarian cancer via TLR4/IKK2/SNARE-dependent exocytosis

…, GCW Man, CH Wong, JHS Lee, SF Yim… - Cancer immunology …, 2020 - AACR
Emerging evidence shows that the efficacy of chemotherapeutic drugs is reliant on their
capability to induce immunogenic cell death (ICD), thus transforming dying tumor cells into …

Genome‐wide gene expression profiling of cervical cancer in Hong Kong women by oligonucleotide microarray

…, GSW Tsao, KWK Lo, SF Yim… - … journal of cancer, 2006 - Wiley Online Library
An analysis of gene expression profiles obtained from cervical cancers was performed to
find those genes most aberrantly expressed. Total RNA was prepared from 29 samples of …

Dysregulated microRNAs in the pathogenesis and progression of cervical neoplasm

T Cheung, KM Man, M Yu, S Yim, NSS Siu, KWK Lo… - Cell Cycle, 2012 - Taylor & Francis
MicroRNAs (miRNAs) play an important role in a variety of physiological as well as
pathophysiological processes, including carcinogenesis. The aim of this study is to identify a distinct …

Genomic aberrations in cervical adenocarcinomas in H ong K ong C hinese women

…, PKS Chan, TH Cheung, SF Yim… - … journal of cancer, 2015 - Wiley Online Library
Although the rates of cervical squamous cell carcinoma have been declining, the rates of
cervical adenocarcinoma are increasing in some countries. Outcomes for advanced cervical …

Epigenetic and genetic alternation of PTEN in cervical neoplasm

TH Cheung, KWK Lo, SF Yim, LKY Chan… - Gynecologic …, 2004 - Elsevier
Objectives. We studied the role of epigenetic and genetic changes of PTEN in the development
of squamous cell carcinoma (SCC) of the uterine cervix and their value as a prognostic …

Transcriptional repression of WEE1 by Kruppel-like factor 2 is involved in DNA damage-induced apoptosis

…, TH Cheung, TKH Chung, KWK Lo, SF Yim… - Oncogene, 2005 - nature.com
Human Kruppel-like factor 2 (KLF2) is a Cys 2/His 2 zinc-finger-containing transcriptional
factor, which is involved in multiple cellular pathways. Utilizing gene expression profiling to …

Natural history of cervical papilloma virus infection in systemic lupus erythematosus—a prospective cohort study

LS Tam, PKS Chan, SC Ho, MMY Yu, SF Yim… - The Journal of …, 2010 - jrheum.org
Objective. To ascertain the incidence, cumulative prevalence, persistence, and clearance of
human papilloma virus (HPV) infection in patients with systemic lupus erythematosus (SLE), …

Liquid biopsy of HPV DNA in cervical cancer

TH Cheung, SF Yim, MY Yu, MJ Worley Jr… - Journal of Clinical …, 2019 - Elsevier
Background A blood test to serve as a tumor marker for cervical cancer would be useful to
clinicians to guide treatment and provide an early signal for recurrence. The development of …