The Italian Society for Osteoporosis, Mineral Metabolism and Bone Diseases (SIOMMMS)
has elaborated the following guidelines about the definition, prevention and treatment of …

Objectives: The aim of this study was to evaluate the trend of the incidence and costs of hip
fractures in Italy. Methods: The incidence of hip fractures after 45 years of age in both females …

Background Denosumab is a fully human monoclonal antibody to the receptor activator of
nuclear factor-κB ligand (RANKL) that blocks its binding to RANK, inhibiting the development …

Background Risedronate increases bone mineral density in elderly women, but whether it
prevents hip fracture is not known. Methods We studied 5445 women 70 to 79 years old who …

Background: Strontium ranelate, a new oral drug shown to reduce vertebral fracture risk in
postmenopausal women with osteoporosis, was studied in the Treatment of Peripheral …

Background Despite its association with disability, death, and increased medical costs,
osteoporosis in men has been relatively neglected as a subject of study. There have been no …

Long‐term use of high‐dose corticosteroids often results in bone loss, which may lead to
osteoporosis‐related fractures. This was a multicenter, double‐blind study in which 290 …

Objective Although oral bisphosphonates are effective treatments for postmenopausal
women with osteoporosis, oral dosing may be unsuitable for some patients. An efficacious …

Dosing convenience is a key element in the effective management of any chronic disease,
and is particularly important in the long-term management of osteoporosis. Less frequent …

Objective Bisphosphonates have slowed the progression of osteoarthritis (OA) in animal
models and have decreased pain in states of high bone turnover. The Knee OA Structural …