THE zinc-finger transcription factor GATA-1 (previously known as GF-1, NF-E1 or Eryf 1 (refs
1-5)) binds to GATA consensus elements in regulatory regions of theα- and β-globin gene …

Genes expressed in erythroid cells contain binding sites for a cell-specific factor believed to
be an important regulator for this haematopoietic lineage. Using high-level transient …

Purpose: Epidermal growth factor receptor (EGFR) mutations related to gefitinib responsiveness
in non–small cell lung cancer have been found recently. Detection of EGFR mutations …

The halophile Vibrio vulnificus is an etiologic agent of human mortality from seafood-borne
infections. We applied whole-genome sequencing and comparative analysis to investigate …

IκB kinase β (IKKβ) is involved in tumor development and progression through activation of
the nuclear factor (NF)-κB pathway. However, the molecular mechanism that regulates IKKβ …

Nosocomial infections caused by antibiotic-resistant Klebsiella pneumoniae are emerging
as a major health problem worldwide, while community-acquired K. pneumoniae infections …

In addition to its role in the recognition of foreign antigens, the T cell receptor (TCR) alpha
gene serves as a model system for studies of developmentally‐regulated, lineage‐specific …

We have determined the entire DNA sequence of pLVPK, which is a 219-kb virulence plasmid
harbored in a bacteremic isolate of Klebsiella pneumoniae. A total of 251 open reading …

Purpose: Mutations in epidermal growth factor receptor (EGFR) can be used to predict the
tumor response of patients receiving gefitinib for non–small cell lung cancer (NSCLC). We …

Importance The antiepileptic drug phenytoin can cause cutaneous adverse reactions, ranging
from maculopapular exanthema to severe cutaneous adverse reactions, which include …