Abatacept mechanism of action: concordance with its clinical profile

…, MJM Calatrava, S Castañeda - … Clínica (English Edition), 2012 - Elsevier
… panel Gabriel Herrero-Beaumont a , María José Martínez Calatrava a , Santos Castañeda b
Santos Castañeda has received education and research grants form Abbott, MSD and Pfizer…

Osteoinmunología: el estudio de la relación entre el sistema inmune y el tejido óseo

L Arboleya, S Castañeda - Reumatología Clínica, 2013 - Elsevier
El tejido óseo es una estructura fuertemente regulada, que desempeña un papel esencial en
diferentes funciones fisiológicas. A través de acciones autocrinas y paracrinas participa en …

IL-6 serum levels predict severity and response to tocilizumab in COVID-19: An observational study

…, C Marcos, E Zamora, PG García, S Castañeda… - Journal of Allergy and …, 2021 - Elsevier
Background Patients with coronavirus disaese 2019 (COVID-19) can develop a cytokine
release syndrome that eventually leads to acute respiratory distress syndrome requiring …

[HTML][HTML] Osteoarthritis associated with estrogen deficiency

JA Roman-Blas, S Castañeda, R Largo… - Arthritis research & …, 2009 - Springer
Osteoarthritis (OA) affects all articular tissues and finally leads to joint failure. Although articular
tissues have long been considered unresponsive to estrogens or their deficiency, there is …

Subchondral bone as a key target for osteoarthritis treatment

S Castañeda, JA Roman-Blas, R Largo… - Biochemical …, 2012 - Elsevier
Osteoarthritis (OA), the most common form of arthritis, is a debilitating and progressive disease
that has become a major cause of disability and impaired quality of life in the elderly. OA …

[HTML][HTML] Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis

M Bellido, L Lugo, JA Roman-Blas, S Castañeda… - Arthritis research & …, 2010 - Springer
Introduction Osteoporosis (OP) increases cartilage damage in a combined rabbit model of
OP and osteoarthritis (OA). Accordingly, we assessed whether microstructure impairment at …

Polymyalgia rheumatica

MA González-Gay, EL Matteson, S Castañeda - The Lancet, 2017 - thelancet.com
Polymyalgia rheumatica is an inflammatory disease that affects the shoulder, the pelvic
girdles, and the neck, usually in individuals older than 50 years. Increases in acute phase …

Ultrasound-detected musculoskeletal urate crystal deposition: which joints and what findings should be assessed for diagnosing gout?

…, A Rodríguez, FJ Cornejo, S Castañeda… - Annals of the …, 2014 - ard.bmj.com
Objective The primary objective of this prospective case-control study was to assess the
diagnostic value of several intra-articular and periarticular ultrasound (US)-detected …

Primary osteoarthritis no longer primary: three subsets with distinct etiological, clinical, and therapeutic characteristics

…, JA Roman-Blas, S Castañeda… - Seminars in arthritis and …, 2009 - Elsevier
BACKGROUND: Osteoarthritis (OA) has been historically divided into primary and
secondary. Primary OA has been defined as an idiopathic condition developing in previously …

[HTML][HTML] Development and feasibility of 4 checklists for the evaluation of comorbidity in patients with rheumatoid arthritis, axial spondyloarthritis and psoriatic arthritis …

S Castañeda, C González, V Villaverde… - … Clínica (English Edition), 2022 - Elsevier
Objetivo Desarrollar y analizar la viabilidad en la práctica diaria de cuatro checklists
relacionados con la comorbilidad, comunes para pacientes con artritis reumatoide (AR), …