The endothelial-mesenchymal transition in systemic sclerosis is induced by endothelin-1 and transforming growth factor-β and may be blocked by macitentan, a dual …
…, F Carubbi, G Pecetti, S Turricchia… - The Journal of …, 2015 - jrheum.org
… Our work is the first demonstration in literature that SSc-EC, under the synergistic effect of
TGF-β and ET-1, may transdifferentiate toward myofibroblasts, thus contributing to fibroblast …
TGF-β and ET-1, may transdifferentiate toward myofibroblasts, thus contributing to fibroblast …
[HTML][HTML] Macitentan in Pulmonary Arterial Hypertension Associated with Connective Tissue Disease (CTD-PAH): Real-World Evidence from the Combined OPUS …
…, MR Lammi, RT Zamanian, S Turricchia… - Cardiology and …, 2024 - Springer
… The CTD-PAH patient population is the largest PAH etiological subgroup after patients with
idiopathic PAH (IPAH) [2, 3], accounting for approximately 15–30% of the PAH population [4,5…
idiopathic PAH (IPAH) [2, 3], accounting for approximately 15–30% of the PAH population [4,5…
Similarity measures for OLAP sessions
… 5.5) is an extension of the soft tf–idf method and is based on the relative importance of
queries within a corpus—in our case, the log of OLAP sessions. The last one (Sect. 5.6) …
queries within a corpus—in our case, the log of OLAP sessions. The last one (Sect. 5.6) …
[HTML][HTML] Adjusting overall survival estimates of macitentan in pulmonary arterial hypertension after treatment switching: results from the SERAPHIN study
L Di Scala, M Bacchi, B Bayer, S Turricchia - Advances in Therapy, 2022 - Springer
… The question that is of interest is what would the overall survival treatment effect have been
in SERAPHIN had treatment switching not occurred? This has previously been explored …
in SERAPHIN had treatment switching not occurred? This has previously been explored …
Land geophysical parameters retrieval using the interference pattern GNSS-R technique
…, G Baroncini-Turricchia… - … on Geoscience and …, 2010 - ieeexplore.ieee.org
… Note that first notch is due to the Brewster’s angle, but new … only one notch which is due to
the Brewster’s angle, the angle at … As it is well known, the Brewster’s angle [22] is computed …
the Brewster’s angle, the angle at … As it is well known, the Brewster’s angle [22] is computed …
OLAP query reformulation in peer-to-peer data warehousing
… , p N s , where μ t = < m t , α t > is a metric of D t , N s is a subset … s , and expr is an expression
involving the measures in N s . This mapping predicate is used to state that whenever m t is …
involving the measures in N s . This mapping predicate is used to state that whenever m t is …
Multi-sprint planning and smooth replanning: An optimization model
… The objective function we adopt is called a free completion measure, because its goal is
not to minimize the project time-span, but rather to maximize the business value perceived by …
not to minimize the project time-span, but rather to maximize the business value perceived by …
A Lagrangian heuristic for sprint planning in agile software development
… The sprint planning phase is critical to ensure the project success, but it is also a difficult
problem because several factors impact on the optimality of a sprint plan, eg, the estimated …
problem because several factors impact on the optimality of a sprint plan, eg, the estimated …
Mining preferences from OLAP query logs for proactive personalization
… First, the log of past MDX queries issued by that user is mined to extract a set of … is selected;
finally, the selected rules are translated into a preference that is used to annotate the user’s …
finally, the selected rules are translated into a preference that is used to annotate the user’s …
Sprint planning optimization in agile data warehouse design
… solution is determined in a time that is fully compatible with the development process (ie,
from some seconds to a few minutes), while for large problems a heuristic solution that is just a …
from some seconds to a few minutes), while for large problems a heuristic solution that is just a …