[HTML][HTML] The role of M1/M2 macrophage polarization in rheumatoid arthritis synovitis

…, R Campitiello, E Gotelli, S Soldano - Frontiers in …, 2022 - frontiersin.org
… Through the interaction with the bridging ligands Gas6 and protein S, MerTK recognizes
apoptotic cells facilitating their phagocytosis; this physiological process of clearance is …

Macrophage M1/M2 polarization and rheumatoid arthritis: a systematic review

S Tardito, G Martinelli, S Soldano, S Paolino… - Autoimmunity …, 2019 - Elsevier
Background and aim Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease;
the clinical manifestations are correlated with continuum multiarticular synovitis, cartilage …

Pathophysiology of systemic sclerosis: current understanding and new insights

M Cutolo, S Soldano, V Smith - Expert review of clinical …, 2019 - Taylor & Francis
… Some risk factors are known and include combination of persistent Raynaud’s phenomenon,
steroid hormone imbalance, selected chemicals, thermal, or other injuries. Endogenous and…

[HTML][HTML] A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement

AC Trombetta, S Soldano, P Contini, V Tomatis… - Respiratory …, 2018 - Springer
… Finally, bivariate Pearson’s correlation was calculated to measure linear relationship
between two variables with ordinal distribution. A p-value lower than 0.05 was considered as …

Use of glucocorticoids and risk of infections

…, C Pizzorni, ME Secchi, S Soldano, S Paolino… - Autoimmunity …, 2008 - Elsevier
Glucocorticoids (GC) exert many complex quantitative and qualitative immunosuppressive
effects that induce cellular immunodeficiency and consequently might increase host …

Peripheral blood perfusion correlates with microvascular abnormalities in systemic sclerosis: a laser-Doppler and nailfold videocapillaroscopy study

M Cutolo, C Ferrone, C Pizzorni, S Soldano… - The Journal of …, 2010 - jrheum.org
… At basal temperature, FBP measurement was started 30–60 s after probe positioning on the
central area of each fingertip, waiting for the minimal variation of the perfusion wave, and the …

Increase in circulating cells coexpressing M1 and M2 macrophage surface markers in patients with systemic sclerosis

S Soldano, AC Trombetta, P Contini… - Annals of the …, 2018 - ard.bmj.com
An M2 pre-eminent phenotype has been postulated for SSc monocytes/macrophages. 2 The
aim of the study was to widen a phenotype characterisation (M1, M2 and mixed M1/M2) of …

[HTML][HTML] CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production

M Cutolo, S Soldano, P Montagna, A Sulli… - Arthritis research & …, 2009 - Springer
Introduction Co-stimulatory signal B7(CD80/CD86):CD28 is needed in order to activate T
cells in immune response. Cytotoxic T lymphocyte-associated antigen-4-immunoglobulin (…

Raynaud's phenomenon and plasma endothelin: correlations with capillaroscopic patterns in systemic sclerosis

A Sulli, S Soldano, C Pizzorni, P Montagna… - The Journal of …, 2009 - jrheum.org
Objective. We evaluated endothelin (ET)-1 plasma levels and some clinical measures in
patients with primary Raynaud’s phenomenon (PRP), and in patients with systemic sclerosis (…

[PDF][PDF] 1, 25-dihydroxyvitamin D3 downregulates aromatase expression and inflammatory cytokines in human macrophages

B Villaggio, S Soldano, M Cutolo - Clin Exp Rheumatol, 2012 - researchgate.net
… (SD) using Tukey-Kramer multiple comparisons non-parametric post-test (ANOVA system)
and box plots, in which the group medians were compared by non-parametric Dunn’s test. All …