User profiles for S. SUMITOMO

Shuji Sumitomo

Department of Rheumatology, Kobe City Medical Center General Hospital
Verified email at umin.ac.jp
Cited by 2320

Roles of LAG3 and EGR2 in regulatory T cells

T Okamura, K Fujio, S Sumitomo… - Annals of the rheumatic …, 2012 - ard.bmj.com
… If you wish to reuse any or all of this article please use the link below which will take you to
the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and …

[PDF][PDF] Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases

…, M Okazaki, H Tsunoda, Y Iwasaki, S Sumitomo… - Cell, 2021 - cell.com
… overlapped with curated IFN signature gene set (one-sided Fisher’s exact test, p = 9.2 3
10 … Behc et’s disease (BD) patients were recruited from the Department of Allergy and …

CD4+CD25LAG3+ regulatory T cells controlled by the transcription factor Egr-2

…, S Sumitomo, H Shoda, S Sakaguchi… - Proceedings of the …, 2009 - National Acad Sciences
Regulatory T cells (Tregs) are engaged in the maintenance of immunological self-tolerance
and immune homeostasis. IL-10 has an important role in maintaining the normal immune …

[HTML][HTML] Immunomodulatory aspects in the progression and treatment of oral malignancy

…, K Mitsudo, Y Muramatsu, S Sumitomo - … Dental Science Review, 2019 - Elsevier
… -tumoral [3,16,17], however, this function may vary depending on the tumor’s diplotype [25]. …
some EMT-inducing tumor antigen(s) is critical for PD-L1 induction via TLR4 on the cells [65]. …

Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis

…, S Sumitomo, K Yamaguchi, Y Nagafuchi, S Nakachi… - Nature …, 2017 - nature.com
… Moreover, the identities of causal cytokine(s) and their genetic drivers remain unclear,
especially in the context of cell specificity. By using all of the predicted genes and their Z case-…

Prognostic value of carcinoembryonic antigen and CYFRA21-1 in patients with pathological stage I non-small cell lung cancer

K Matsuoka, S Sumitomo, N Nakashima… - European journal of …, 2007 - academic.oup.com
… Serum levels of CEA and CYFRA21-1 higher than 5.0 and 2.8 ng/ml, respectively, were
considered as positive according to the manufacture’s instructions. Results: The histological …

[HTML][HTML] TGF-β3-expressing CD4+CD25LAG3+ regulatory T cells control humoral immune responses

T Okamura, S Sumitomo, K Morita, Y Iwasaki… - Nature …, 2015 - nature.com
… All other statistical differences were determined using the two-tailed Student’s t-test. If the
variance was unequal, Welch’s correction was applied to Student’s t-test. Differences were …

The HAUSP gene plays an important role in non‐small cell lung carcinogenesis through p53‐dependent pathways

…, M Ueno, N Nakashima, S Sumitomo - The Journal of …, 2006 - Wiley Online Library
… to 32 PCR amplification cycles of 60 s at 94 C, 60 s at 55 C, and 90 s at 72 C. For p21, bax,
… to 31 PCR amplification cycles of 60 s at 94 C, 60 s at 60 C, and 90 s at 72 C. Preparations of …

Egr‐2 transcription factor is required for Blimp‐1‐mediated IL‐10 production in IL‐27‐stimulated CD4+ T cells

…, T Okamura, A Yanai, S Sumitomo… - European journal of …, 2013 - Wiley Online Library
Interleukin‐27 (IL‐27) suppresses immune responses through inhibition of the development
of IL‐17 producing Th17 cells and induction of IL‐10 production. We previously showed that …

[HTML][HTML] Transforming Growth Factor-β and Interleukin-10 Synergistically Regulate Humoral Immunity via Modulating Metabolic Signals

…, T Okamura, K Morita, Y Iwasaki, S Sumitomo… - Frontiers in …, 2018 - frontiersin.org
… A comparison of more than two group means was analyzed by ANOVA with Bonferroni’s or
Holm–Sidak’s multiple comparison tests. A comparison of two group means was analyzed by …