… The results of the study have not yet been published, but the preliminary data are available
on the sponsor’s website 104 and in the trial register (NCT02092467). The initial preliminary …

Bone homeostasis is maintained by a balance between bone resorption by osteoclasts and
bone formation by osteoblasts. Osteoblasts not only play a central role in bone formation by …

CD4 + helper T cells play crucial roles for host defense and immune-mediated disease by
their ability to differentiate into specialized subsets. These subsets attain restricted patterns of …

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Follicular helper T (Tfh) cells comprise an important subset of helper T cells; however, their
relationship with other helper lineages is incompletely understood. Herein, we showed …

… Collectively, these data indicate that miRNA is important in preserving the phenotypic
stability of helper T cells and raise the question of which specific miRNA(s) is (are) responsible. …

Signaling pathways are intimately involved in cellular differentiation, allowing cells to respond
to their environment by regulating gene expression. Although enhancers are recognized …

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Objectives. Systemic lupus erythematosus (SLE) is an autoimmune disease characterized
by autoreactive T cells and polyclonally activated B cells that produce autoantibodies. Five …

… Similarly, two other hormones, prolactin (PRL) and growth hormone (GH), were discovered
in the 1930 s and 1950 s, respectively, with no hint that they were related to IFNs. In 1969, the …