Refolding of therapeutic proteins produced in Escherichia coli as inclusion bodies

S Misawa, I Kumagai - Peptide Science, 1999 - Wiley Online Library
… We have shown that porcine muscle adenylate kinase is expressed in E. coli as inclusion …
For this purpose, Gdn-HCl is usually preferable to urea for two reasons.First, Gdn-HCl is a …

Antibiotic Resistance of Helicobacter pylori Strains in Japanese Children

…, H Udagawa, T Shimizu, S Maisawa… - Journal of Clinical …, 2002 - Am Soc Microbiol
… The present study has shown that primary resistance to clarithromycin is frequently observed
in … clarithromycin and azithromycin is nearly complete in H. pylori isolates. Glupczynski et al. …

[HTML][HTML] Diagnosis and management of transthyretin familial amyloid polyneuropathy in Japan: red-flag symptom clusters and treatment algorithm

Y Sekijima, M Ueda, H Koike, S Misawa, T Ishii… - Orphanet journal of rare …, 2018 - Springer
… Val50Met]) is the most commonly observed mutation, the only one found in large foci of
patients, and is associated primarily with neuropathy [1, 10]. TTR gene mutations destabilize TTR…

Treatment for POEMS (polyneuropathy, organomegaly, endocrinopathy, M‐protein, and skin changes) syndrome

…, A Dispenzieri, K Arimura, S Misawa… - Cochrane Database …, 2012 - cochranelibrary.com
… , is likely to be responsible for most of the characteristic symptoms. POEMS syndrome …
There is a need for efficacious therapy to improve prognosis. This is the first update of a …

Internal tandem duplication of the flt3 gene found in acute myeloid leukemia.

…, K Kashima, Y Sonoda, T Fujimoto, S Misawa - Leukemia, 1996 - europepmc.org
We analyzed mRNA expression of the flt3 gene in 30 patients with acute myeloid leukemia (AML)
and 50 with acute lymphoblastic leukemia (ALL). Using reverse transcriptase-…

The prevalence of Helicobacter pylori in Japanese children with gastritis or peptic ulcer disease

…, M Konno, S Maisawa, S Toyoda, H Tajiri, S Ida… - Journal of …, 2004 - Springer
is consistent with that analysis, showing that H. pylori is the most important causal factor
for the development of DU in childhood. It has been hypothesized that gastric metaplasia is

Improvements on the electrical and luminescent properties of reactive molecular beam epitaxially grown GaN films by using AlN‐coated sapphire substrates

S Yoshida, S Misawa, S Gonda - Applied Physics Letters, 1983 - pubs.aip.org
… c axis ofGaN is normal to the substrate surface and the a axis of GaN is parallel to … is in the
plane of substrate surface and is parallel to c' [01 Ii ] axis of sapphire, and the b axis of GaN is

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological …

S Yokota, H Kiyoi, M Nakao, T Iwai, S Misawa, T Okuda… - Leukemia, 1997 - nature.com
In this study, we examined a large number of patients to clarify the distribution and frequency
of a recently described FLT3 tandem duplication among hematopoietic malignancies, …

Overexpression of spermidine synthase enhances tolerance to multiple environmental stresses and up-regulates the expression of various stress-regulated genes in …

…, K Nada, S Misawa, I Ihara, S Tachibana - Plant and Cell …, 2004 - academic.oup.com
… However, such attempts are still limited and there is no information available on the stress
responses of transgenic plants overexpressing the SPDS transgene. In addition, little attention …

Association Between Gastric Atrophy and Helicobacter pylori Infection in Japanese Children: A Retrospective Multicenter Study

…, T Minoura, M Konno, S Maisawa, S Toyoda… - Digestive diseases and …, 2006 - Springer
… pylori infection is often associated with chronic gastritis and sometimes with gastroduodenal
… pylori gastritis is thought to be responsible for different clinical outcomes (7–9). Chronic H. …