Early mortality in a multinational systemic sclerosis inception cohort

…, N Khalidi, M Larché, S LeClercq, S Ligier… - Arthritis & …, 2017 - Wiley Online Library
Objective To determine mortality and causes of death in a multinational inception cohort of
subjects with systemic sclerosis (SSc). Methods We quantified mortality as standardized …

The clinimetric properties of the World Health Organization Disability Assessment Schedule II in early inflammatory arthritis

…, H Kang, M Kapusta, S Ligier… - Arthritis Care & …, 2008 - Wiley Online Library
Objective To assess the clinimetric properties of a new health‐related quality of life (HRQOL)
instrument, the World Health Organization Disability Assessment Schedule II (WHODAS II), …

Calcinosis is associated with digital ischaemia in systemic sclerosis—a longitudinal study

…, JP Mathieu, S Ligier, T Grodzicky, S LeClercq… - …, 2016 - academic.oup.com
Objective. To determine if ischaemia is a causal factor in the development of calcinosis in
SSc. Methods. Patients with SSc were assessed yearly. Physicians reported the presence of …

[HTML][HTML] The impact of pain and itch on functioning and health-related quality of life in systemic sclerosis: an exploratory study

…, A Masseto, E Sutton, JP Mathieu, S Ligier… - Journal of pain and …, 2016 - Elsevier
Context Pain and itch are common symptoms reported by patients with systemic sclerosis (SSc;
scleroderma), which can markedly diminish function and health-related quality of life (…

2013 American College of Rheumatology/European League against rheumatism classification criteria for systemic sclerosis outperform the 1980 criteria: data from the …

…, S Ligier, T Grodzicky, S LeClercq… - Arthritis care & …, 2015 - Wiley Online Library
Objective The goal of this study was to determine the sensitivity of the new 2013 classification
criteria for systemic sclerosis (SSc; scleroderma) in an independent cohort of SSc subjects …

Bicaudal D2 is a novel autoantibody target in systemic sclerosis that shares a key epitope with CENP-A but has a distinct clinical phenotype

…, M Hudson, S Ligier, T Grodzicky, S LeClercq… - Autoimmunity …, 2018 - Elsevier
We studied the clinical correlations and epitopes of autoantibodies directed to a novel
autoantigen, Bicaudal D (BICD2), in systemic sclerosis (SSc) and reviewed its relationship to …

Symptoms of depression predict the trajectory of pain among patients with early inflammatory arthritis: a path analysis approach to assessing change

…, S Ligier, JP Mathieu, H Menard, S Mercille… - The Journal of …, 2009 - jrheum.org
… exist to assess disease activity in RA, these include subjective factors such as tender joint
count and patient global assessment of disease activity that may be affected by the patient’s

A new antibody in rheumatoid arthritis targeting glycated IgG: IgM anti-IgG-AGE.

S Ligier, PR Fortin, MM Newkirk - British journal of …, 1998 - academic.oup.com
Hyperglycaemia and/or oxidative stress can cause IgG to be modified by advanced glycation
end products (AGE). Three patients with aggressive rheumatoid arthritis (RA) and vasculitis …

Corticotropin releasing hormone (CRH) antagonist attenuates adjuvant induced arthritis: role of CRH in peripheral inflammation.

…, C Contoreggi, MG Isaac, S Ligier… - The Journal of …, 2002 - jrheum.org
… Arthritis was induced in both antalarmin and vehicle treated LEW/N and F344/N rats by
subcutaneous injections at the base of the tail of incomplete Freund’s adjuvant containing 10 mg/…

Pilot clinical trial of dehydroepiandrosterone (DHEA) versus placebo for Sjögren's syndrome

…, RA Leakan, JA Smith, M Grisius, S Ligier… - Arthritis Care & …, 2004 - Wiley Online Library
Objective To screen for potential efficacy and assess feasibility and safety of
dehydroepiandrosterone (DHEA) as a treatment for Sjögren's syndrome (SS). Methods A 24‐week …