Biocatalytic asymmetric synthesis of (R)‐1‐tetralol using Lactobacillus paracasei BD101

E Kalay, E Şahin - Chirality, 2021 - Wiley Online Library
Asymmetric bioreduction of ketones is a fundamental process in the production of organic
molecules. Compounds containing tetralone rings are found in the structure of many …

Biocatalytic asymmetric synthesis of (S)-1-indanol using Lactobacillus paracasei BD71

E Kalay, E Dertli, E Şahin - Biocatalysis and Biotransformation, 2022 - Taylor & Francis
… (S)-2 by using whole-cell biocatalyst. To our knowledge, enantiopure synthesis of (S)-2 in …
of this study is synthesis of (S)-2 in high yield and conversion using a whole-cell biocatalyst. …

Regioselective asymmetric bioreduction of trans‐4‐phenylbut‐3‐en‐2‐one by whole‐cell of Weissella cibaria N9 biocatalyst

E Kalay, E Şahin - Chirality, 2021 - Wiley Online Library
… In addition, to our knowledge, this is the first report on production of (S,E)‐2 using whole‐cell
biocatalyst in excellent yield, conversion with enantiopure form and at gram scale. These …

Design, synthesis, antioxidant and anticholinesterase activities of novel isonicotinic hydrazide-hydrazone derivatives

Ö Aslanhan, E Kalay, FS Tokalı, Z Can… - Journal of Molecular …, 2023 - Elsevier
The design and synthesis of hydrazone derivatives are increasing in popularity day by day
due to the significant biological activities of this scaffold. In the present study, twelve novel …

Synthesis, biological evaluation, and in silico study of novel library sulfonates containing quinazolin‐4(3H)‐one derivatives as potential aldose reductase inhibitors

…, E Kalay, K Şendil, Ş Beydemir - Drug Development …, 2022 - Wiley Online Library
A series of novel sulfonates containing quinazolin‐4(3H)‐one ring derivatives was
designed to inhibit aldose reductase (ALR2, EC 1.1.1.21). Novel quinazolinone derivatives (1–21) …

Synthesis and characterization of novel acyl hydrazones derived from vanillin as potential aldose reductase inhibitors

Y Demir, FS Tokalı, E Kalay, C Türkeş, P Tokalı… - Molecular Diversity, 2023 - Springer
In the polyol pathway, aldose reductase (AR) catalyzes the formation of sorbitol from glucose.
In order to detoxify some dangerous aldehydes, AR is essential. However, due to the …

Synthesis of calix [4] azacrown substituted sulphonamides with antioxidant, acetylcholinesterase, butyrylcholinesterase, tyrosinase and carbonic anhydrase inhibitory …

M Oguz, E Kalay, S Akocak, A Nocentini… - Journal of enzyme …, 2020 - Taylor & Francis
… The imbalance in AChE activity can cause various types of neurodegenerative pathologies
such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). Butyrylcholinesterase (…

Asymmetric reduction of prochiral aromatic and hetero aromatic ketones using whole-cell of Lactobacillus senmaizukei biocatalyst

NS Çolak, E Kalay, E Şahin - Synthetic Communications, 2021 - Taylor & Francis
Asymmetric bioreduction of aromatic and heteroaromatic ketones is an important process in
the production of precursors of biologically active molecules. In this study, the bioreduction …

The influence of band bending phenomenon on photocatalytic Suzuki-Miyaura coupling reaction: The case of AgPd alloy nanoparticles supported on graphitic carbon …

O Altan, E Kalay - Applied Surface Science, 2022 - Elsevier
… Author links open overlay panel Orhan Altan a b , Erbay Kalay c … In addition, the high-resolution
XPS spectra of C 1 s, N 1 s, Ag 3d and Pd 3d core levels of the Mott- Schottky catalysts …

Black phosphorus as a metal-free, visible-light-active heterogeneous photoredox catalyst for the direct C–H arylation of heteroarenes

E Kalay, H Küçükkeçeci, H Kilic, Ö Metin - Chemical communications, 2020 - pubs.rsc.org
Black phosphorus (BP) is for the first time employed as a metal-free, heterogeneous
photoredox catalyst for the direct C–H arylation of heteroarenes with aryl diazonium salts. The …