Osteoarthritis (OA) is a degenerative joint disease that progressively causes loss of joint
function and is the leading source of physical disability and impaired quality of life in …

… Thus OA, which “sends” a half-million Americans to total joint replacement surgeries each
year, will continue to burden our society’s aging and expanding population in increasing …

Although colchicine has been a focus of research, debate, and controversy for thousands of
years, the US Food and Drug Administration just approved it in 2009. Over the past decade, …

… Triazol reagent (GIBCO-BRL) was used according to the manufacturer’s instructions. An
additional final precipitation in LiCl was performed to further purify RNA from contaminant DNA. …

Objective To evaluate whether gene expression profiles could serve as biomarkers of
symptomatic knee osteoarthritis (OA) by examining gene expression profiles in peripheral blood …

BACKGROUND: Patients with gout have comorbidities, but the impact of these comorbidities
on treatment has not been studied. METHODS: A total of 575 patients with gout were …

Osteoarthritis (OA) is often a progressive and disabling disease resulting from a combination
of risk factors, including age, genetics, trauma, and knee alignment, as well as an …

… Colchicine’s mechanisms of action are multiple, and more complex than previously …
Colchicine’s anti-inflammatory effects hold promise for prevention/management of cardiovascular …

… of knee osteoarthritis - Krasnokutsky - 2011 - Arthritis & Rheumatism - Wiley Online Library
… Krasnokutsky had full access to all of the data in the study and takes responsibility for the …

… Over the past several decades, gout’s prevalence has risen in parallel with such current …
We summarize the known facts about gout’s relationship with five major components and/or …