Objectives Identifying blood-based biomarkers that predict treatment response in RA is a
clinical priority. We investigated differential DNA methylation as a candidate biomarker of …

Objective. The importance of contextual factors (CF) for appropriate patient-specific care is
widely acknowledged. However, evidence in clinical trials on how CF influence outcomes …

Background/Aims Recent translational advances in genetics report the ability to accurately
predict the diagnosis of patients presenting with synovitis, providing potential to accelerate …

Background Methotrexate (MTX) is the first-line disease modifying anti-rheumatic drug for the
treatment of rheumatoid arthritis (RA). However, many patients do not respond adequately …

Background Living with RA confers substantial uncertainty about the long-term outcomes of
the disease and the occurrence of possible medication associated adverse events (ADEs). …

In order for fusion reactors to be a viable sustainable energy source, the divertor plates
need to be protected from the high heat loads expected to be produced within the next …

Background Rheumatologists are the primary prescribers of methotrexate (MTX) for the
treatment of rheumatoid arthritis (RA) in the United Kingdom (UK), however rheumatologists9 …

Background Anti-citrullinated protein antibody (ACPA) immune response occurs several years
prior to the diagnosis of rheumatoid arthritis (RA). However, limited data are available on …

Background/Aims Recent global health crises have highlighted the importance of socioeconomic
(SE) inequalities and its influence on health provision and outcomes. The impact of SE …

Background: Several individual dietary components have been associated with the risk of RA
and recent studies have suggested that dietary indices, which account for the consumption …