Differential DNA methylation correlates with response to methotrexate in rheumatoid arthritis
Objectives Identifying blood-based biomarkers that predict treatment response in RA is a
clinical priority. We investigated differential DNA methylation as a candidate biomarker of …
clinical priority. We investigated differential DNA methylation as a candidate biomarker of …
An OMERACT initiative toward consensus to identify and characterize candidate contextual factors: report from the contextual factors working group
…, CA Flurey, N Milman, SM Verstappen… - The Journal of …, 2017 - jrheum.org
Objective. The importance of contextual factors (CF) for appropriate patient-specific care is
widely acknowledged. However, evidence in clinical trials on how CF influence outcomes …
widely acknowledged. However, evidence in clinical trials on how CF influence outcomes …
P042 Using a Genetic PROBability tool (G-PROB) to aid diagnosis of patients with inflammatory arthritis: results from the Norfolk Arthritis Register
…, M Yates, M Soomro, SM Verstappen… - …, 2023 - academic.oup.com
Background/Aims Recent translational advances in genetics report the ability to accurately
predict the diagnosis of patients presenting with synovitis, providing potential to accelerate …
predict the diagnosis of patients presenting with synovitis, providing potential to accelerate …
THU0001 differential methylation as a potential biomarker of methotrexate response in patients with rheumatoid arthritis
Background Methotrexate (MTX) is the first-line disease modifying anti-rheumatic drug for the
treatment of rheumatoid arthritis (RA). However, many patients do not respond adequately …
treatment of rheumatoid arthritis (RA). However, many patients do not respond adequately …
THU0168 Patients' positive beliefs and certainty predict methotrexate adherence in a rheumatoid arthritis cohort: the rams study
HF Hope, K Hyrich, F Varney, S Wilkes, SM Verstappen… - 2017 - ard.bmj.com
Background Living with RA confers substantial uncertainty about the long-term outcomes of
the disease and the occurrence of possible medication associated adverse events (ADEs). …
the disease and the occurrence of possible medication associated adverse events (ADEs). …
[PDF][PDF] Spectroscopic determination of the radial electric potential profile within a Magnum-PSI plasma
JDE Verstappen - Applied Physics, 2023 - research.tue.nl
In order for fusion reactors to be a viable sustainable energy source, the divertor plates
need to be protected from the high heat loads expected to be produced within the next …
need to be protected from the high heat loads expected to be produced within the next …
THU0192 Informing patients about methotrexate for the treatment of rheumatoid arthritis with patients in the united kingdom–a survey of rheumatologists' strategies
HF Hope, SM Verstappen, L Cordingley, K Hyrich - 2017 - ard.bmj.com
Background Rheumatologists are the primary prescribers of methotrexate (MTX) for the
treatment of rheumatoid arthritis (RA) in the United Kingdom (UK), however rheumatologists9 …
treatment of rheumatoid arthritis (RA) in the United Kingdom (UK), however rheumatologists9 …
OP0268 Anti-Citrullinated Protein Antibody (ACPA) Status in the General Population and as a Predictor of Future Inflammatory Polyarthritis: The EPIC-2-Noar Study
SM Verstappen, JC Sergeant, RN Luben, A Bhaniani… - 2015 - ard.bmj.com
Background Anti-citrullinated protein antibody (ACPA) immune response occurs several years
prior to the diagnosis of rheumatoid arthritis (RA). However, limited data are available on …
prior to the diagnosis of rheumatoid arthritis (RA). However, limited data are available on …
P144 Socioeconomic deprivation is associated with reduced response and lower treatment persistence with anti-TNF therapies in people with rheumatoid arthritis
…, A Bosworth, J Galloway, SM Verstappen… - …, 2023 - academic.oup.com
Background/Aims Recent global health crises have highlighted the importance of socioeconomic
(SE) inequalities and its influence on health provision and outcomes. The impact of SE …
(SE) inequalities and its influence on health provision and outcomes. The impact of SE …
O14 pro-inflammatory diets are associated with increased c-reactive protein and subsequent rheumatoid arthritis in the european investigation of cancer: norfolk …
E Sayers, JR Dainty, M Yates, SM Verstappen… - …, 2019 - academic.oup.com
Background: Several individual dietary components have been associated with the risk of RA
and recent studies have suggested that dietary indices, which account for the consumption …
and recent studies have suggested that dietary indices, which account for the consumption …