Glucocorticoids (GCs), which are used in the treatment of immune-mediated inflammatory
diseases, inhibit the expression of many inflammatory mediators. They can also induce the …

The stress-activated protein kinase p38 stabilizes a number of mRNAs encoding
inflammatory mediators, such as cyclooxygenase 2 (Cox-2). In HeLa cells the anti-inflammatory …

Phosphoinositide (PI) 3-kinase was first observed in 1984 as a minor inositol lipid kinase
activity associated with immunoprecipitated oncogene products (eg Src, Abl and polyoma mT …

Innate immune responses are critically dependent on MAPK (mitogen-activated protein kinase)
signalling pathways, in particular JNK (c-Jun N-terminal kinase) and p38 MAPK. Both of …

Objectives To establish if changes in Th1/Th17 cell populations previously reported in
experimental arthritis occur in patients with rheumatoid arthritis (RA) treated with anti-tumour …

Human phosphoglucomutase 3 (PGM3) catalyzes the conversion of N-acetyl-glucosamine (GlcNAc)-6-phosphate
into GlcNAc-1-phosphate during the synthesis of uridine diphosphate (…

Inborn errors of immunity (IEI) are a genetically heterogeneous group of disorders with a
broad clinical spectrum. Identification of molecular and functional bases of these disorders is …

The aqueous chlorination of (chloro)phenols is one of the best-studied reactions in the
environmental literature. Previous researchers have attributed these reactions to two chlorine …

In order to assess the effect of fine fraction of Reclaimed Asphalt Pavement (RAP) aggregates
as an alternative to natural fine aggregates (NA), cement mortar samples were prepared …

… Author links open overlay panel Sarah Mariam Abraham , GDRN Ransinchung … The effect
of gradation of RAP aggregates was studied by Abraham SM and Ransinchung GDRN [16], …