Autoantibodies as predictive tools in systemic sclerosis

SI Nihtyanova, CP Denton - Nature reviews rheumatology, 2010 - nature.com
The pathogenetic role of autoantibodies in systemic sclerosis (SSc) remains unclear, but
these autoantibodies have been established as strong predictors of disease outcome and the …

Prediction of pulmonary complications and long‐term survival in systemic sclerosis

SI Nihtyanova, BE Schreiber, VH Ong… - Arthritis & …, 2014 - Wiley Online Library
Objective To assess survival and incidence of organ‐based complications in a large single‐center
cohort of unselected systemic sclerosis (SSc) patients, and to explore predictors of …

Improved survival in systemic sclerosis is associated with better ascertainment of internal organ disease: a retrospective cohort study

SI Nihtyanova, EC Tang, JG Coghlan… - … Journal of Medicine, 2010 - academic.oup.com
Background: Systemic sclerosis (SSc) has high mortality and morbidity. Current management
focuses on early detection and treatment of organ-based manifestations. Aim: To …

[PDF][PDF] Current management strategies for systemic sclerosis

SI Nihtyanova, VH Ong, CP Denton - Clin Exp Rheumatol, 2014 - clinexprheumatol.org
… strategies for systemic sclerosis / SI Nihtyanova et al. … Current management strategies for
systemic sclerosis / SI Nihtyanova et al. … strategies for systemic sclerosis / SI Nihtyanova et al. …

Mycophenolate mofetil in diffuse cutaneous systemic sclerosis—a retrospective analysis

SI Nihtyanova, GM Brough, CM Black… - Rheumatology, 2007 - academic.oup.com
Objectives . We have assessed indications, duration and tolerability of treatment with
mycophenolate mofetil (MMF) in patients with diffuse cutaneous systemic sclerosis (dcSSc), and …

Clinical burden of digital vasculopathy in limited and diffuse cutaneous systemic sclerosis

SI Nihtyanova, GM Brough, CM Black… - Annals of the rheumatic …, 2008 - ard.bmj.com
Background: Vascular damage is a key pathological process in systemic sclerosis (SSc)
and accounts for significant disease-related morbidity. To determine the clinical burden of …

Using autoantibodies and cutaneous subset to develop outcome‐based disease classification in systemic sclerosis

SI Nihtyanova, A Sari, JC Harvey, A Leslie… - Arthritis & …, 2020 - Wiley Online Library
Objective To describe the associations between autoantibodies, clinical presentation, and
outcomes among patients with systemic sclerosis ( SS c) in order to develop a novel SS c …

Sustained benefit from intravenous immunoglobulin therapy for gastrointestinal involvement in systemic sclerosis

J Raja, SI Nihtyanova, CD Murray, CP Denton… - …, 2016 - academic.oup.com
Objective. IVIG is known to confer significant benefit in rheumatologic conditions, including
inflammatory myopathy. This study aimed to assess the efficacy of IVIG across different …

Characteristics and survival of anti–U1 RNP antibody–positive patients with connective tissue disease–associated pulmonary arterial hypertension

…, BM Lynch, BE Schreiber, SI Nihtyanova… - Arthritis & …, 2016 - Wiley Online Library
Objective Pulmonary arterial hypertension (PAH) is a severe complication of connective
tissue diseases (CTDs). This study aimed to investigate the clinical and hemodynamic …

Impact of hallmark autoantibody reactivity on early diagnosis in scleroderma

P Moinzadeh, SI Nihtyanova, K Howell, VH Ong… - Clinical reviews in …, 2012 - Springer
Raynaud's phenomenon often precedes the diagnosis of systemic sclerosis and is the first
symptom of the disease in many cases. Antinuclear antibody positivity can assist in the early …