User profiles for Ruth M Barrientos

Ruth M. Barrientos

Associate Professor, The Ohio State University
Verified email at osumc.edu
Cited by 7660

The impact of nutrition on COVID-19 susceptibility and long-term consequences

MJ Butler, RM Barrientos - Brain, behavior, and immunity, 2020 - Elsevier
While all groups are affected by the COVID-19 pandemic, the elderly, underrepresented
minorities, and those with underlying medical conditions are at the greatest risk. The high rate of …

mRNA up-regulation of MHC II and pivotal pro-inflammatory genes in normal brain aging

MG Frank, RM Barrientos, JC Biedenkapp, JW Rudy… - Neurobiology of …, 2006 - Elsevier
In normal brain aging, CNS resident macrophages exhibit increased expression of major
histocompatibility complex (MHC) II expression. However, the transcriptional basis for this …

The role of the dorsal hippocampus in the acquisition and retrieval of context memory representations

P Matus-Amat, EA Higgins, RM Barrientos… - Journal of …, 2004 - Soc Neuroscience
It is argued that the hippocampus contributes to contextual fear conditioning by supporting the
acquisition of a conjunctive memory representation of context, which associates with shock…

Peripheral infection and aging interact to impair hippocampal memory consolidation

RM Barrientos, EA Higgins, JC Biedenkapp… - Neurobiology of …, 2006 - Elsevier
We report that a peripheral injection of Escherichia coli produces both anterograde and
retrograde amnesia in 24 month old, but not 3 month old rats for memories that depend on the …

Hippocampal formation supports conditioning to memory of a context.

JW Rudy, RM Barrientos, RC O'reilly - Behavioral neuroscience, 2002 - psycnet.apa.org
It has been proposed that contextual fear conditioning depends on 2 processes:(a)
construction of a conjunctive representation of the features that make up the context and (b) …

Memory for context is impaired by a post context exposure injection of interleukin-1 beta into dorsal hippocampus

RM Barrientos, EA Higgins, DB Sprunger… - Behavioural brain …, 2002 - Elsevier
Prior research has revealed that treatments that elevate the level of the pro-inflammatory
cytokine IL-1β in the brain, if given after training, impair contextual but not auditory-cue fear …

Time course of hippocampal IL-1 β and memory consolidation impairments in aging rats following peripheral infection

RM Barrientos, MG Frank, AM Hein, EA Higgins… - Brain, behavior, and …, 2009 - Elsevier
We previously reported that aging F344XBN rats are more vulnerable to disruptions of
memory consolidation processes following an injection of Escherichia coli than are young rats. …

Intracisternal interleukin-1 receptor antagonist prevents postoperative cognitive decline and neuroinflammatory response in aged rats

RM Barrientos, AM Hein, MG Frank… - Journal of …, 2012 - Soc Neuroscience
To investigate the role of the pro-inflammatory cytokine interleukin-1β (IL-1β) in postoperative
cognitive dysfunction (POCD) in aged rats, we used laparotomy to mimic human …

[HTML][HTML] Food for thought: how nutrition impacts cognition and emotion

…, A Korosi, S Layé, B Shukitt-Hale, RM Barrientos - npj Science of …, 2017 - nature.com
More than one-third of American adults are obese and statistics are similar worldwide.
Caloric intake and diet composition have large and lasting effects on cognition and emotion, …

BDNF mRNA expression in rat hippocampus following contextual learning is blocked by intrahippocampal IL-1β administration

RM Barrientos, DB Sprunger, S Campeau… - Journal of …, 2004 - Elsevier
The present study examined the modulating effects of an intrahippocampal injection of
interleukin-1β (IL-1β) on brain-derived neurotrophic factor (BDNF) mRNA expression 0.5, 2, 4, …