This is an encyclopedic textbook covering the major areas of interest to pediatric rheumatologists.
As such it suffers from the problems of any encyclopedic work. While virtually every …

Juvenile idiopathic arthritis (JIA) is defined by the International League of Associations for
Rheumatology (ILAR) as arthritis of unknown etiology that begins before the sixteenth birthday …

Inflammasomes are innate immune sensors that respond to pathogen- and damage-associated
signals with caspase-1 activation, interleukin (IL)-1β and IL-18 secretion, and …

Purpose Genetic testing is an integral diagnostic component of pediatric medicine. Standard
of care is often a time-consuming stepwise approach involving chromosomal microarray …

Systemic autoinflammatory diseases are driven by abnormal activation of innate immunity 1
. Herein we describe a new disease caused by high-penetrance heterozygous germline …

The American College of Rheumatology (ACR) published treatment recommendations for
juvenile idiopathic arthritis (JIA) in 2011 (1). These recommendations represented the first …

ContextThe treatment of juvenile idiopathic arthritis (JIA) has changed markedly in the last
15 years. Many children with JIA are not treated by pediatric rheumatologists.ObjectiveTo …

… As in many other connective tissue diseases, JLS mainly involves females with a F: M ratio of
2–3: 1 [2••,22,23] . … In adults, immunoglobulin M (IgM) rheumatoid factor is present in 30% of …

Objective. To revise the current juvenile idiopathic arthritis (JIA) International League of
Associations for Rheumatology (ILAR) classification criteria with an evidence-based approach, …

Offering up-to-date, comprehensive coverage of disease progression, diagnosis, management,
and prognosis, Textbook of Pediatric Rheumatology is the definitive reference in the field…