Mapping and predicting mortality from systemic sclerosis
…, F Iannone, LP Ananieva, R Hesselstrand… - Annals of the …, 2017 - ard.bmj.com
Objectives To determine the causes of death and risk factors in systemic sclerosis (SSc).
Methods Between 2000 and 2011, we examined the death certificates of all French patients …
Methods Between 2000 and 2011, we examined the death certificates of all French patients …
Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
…, J van Laar, A Herrick, J Worthington, R Hesselstrand… - Nature …, 2010 - nature.com
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and
internal organs that leads to profound disability and premature death. To identify new SSc …
internal organs that leads to profound disability and premature death. To identify new SSc …
[HTML][HTML] Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis
…, M Wenink, R Huijbens, R Hesselstrand… - New England journal …, 2014 - Mass Medical Soc
Background Plasmacytoid dendritic cells have been implicated in the pathogenesis of
systemic sclerosis through mechanisms beyond the previously suggested production of type I …
systemic sclerosis through mechanisms beyond the previously suggested production of type I …
Mortality and causes of death in a Swedish series of systemic sclerosis patients
R Hesselstrand, A Scheja, A Åkesson - Annals of the rheumatic …, 1998 - ard.bmj.com
OBJECTIVES To analyse survival rates and the causes of death in a systemic sclerosis (SSc)
population, and to evaluate the occurrence of fatal malignant neoplasms and their possible …
population, and to evaluate the occurrence of fatal malignant neoplasms and their possible …
[HTML][HTML] Standardisation of nailfold capillaroscopy for the assessment of patients with Raynaud's phenomenon and systemic sclerosis
…, M Gutierrez, G Gyger, E Hachulla, R Hesselstrand… - Autoimmunity …, 2020 - Elsevier
Capillaroscopy is a non-invasive and safe tool which allows the evaluation of the morphology
of the microcirculation. Since its recent incorporation in the 2013 American College of …
of the microcirculation. Since its recent incorporation in the 2013 American College of …
International consensus criteria for the diagnosis of Raynaud's phenomenon
…, Y Allanore, S Guiducci, R Hesselstrand… - Journal of …, 2014 - Elsevier
Vasoconstriction accompanied by changes in skin color is a normal physiologic response to
cold. The distinction between this normal physiology and Raynaud's phenomenon (RP) has …
cold. The distinction between this normal physiology and Raynaud's phenomenon (RP) has …
[HTML][HTML] Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy
…, P Airo, J van Laar, J Worthington, R Hesselstrand… - PLoS …, 2011 - journals.plos.org
The aim of this study was to determine, through a genome-wide association study (GWAS),
the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis …
the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis …
[HTML][HTML] The pronounced Th17 profile in systemic sclerosis (SSc) together with intracellular expression of TGFβ and IFNγ distinguishes SSc phenotypes
…, L van Bon, J Broen, A Hussiani, R Hesselstrand… - PloS one, 2009 - journals.plos.org
Background Systemic sclerosis (SSc) is an autoimmune disease where controversy on Th1/Th2
balance dominates. We investigated whether the recently discovered Th17 pattern was …
balance dominates. We investigated whether the recently discovered Th17 pattern was …
[PDF][PDF] Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis
…, AE Voskuyl, AJ Schuerwegh, R Hesselstrand… - The American Journal of …, 2014 - cell.com
In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with
the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human …
the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human …
The association of antinuclear antibodies with organ involvement and survival in systemic sclerosis
R Hesselstrand, A Scheja, GQ Shen, A Wiik… - …, 2003 - academic.oup.com
Objectives. To study the frequency and specificity of antinuclear antibodies (ANA) and their
association with internal organ involvement and survival in systemic sclerosis (SSc). Methods…
association with internal organ involvement and survival in systemic sclerosis (SSc). Methods…