Objectives To determine the causes of death and risk factors in systemic sclerosis (SSc).
Methods Between 2000 and 2011, we examined the death certificates of all French patients …

Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and
internal organs that leads to profound disability and premature death. To identify new SSc …

Background Plasmacytoid dendritic cells have been implicated in the pathogenesis of
systemic sclerosis through mechanisms beyond the previously suggested production of type I …

OBJECTIVES To analyse survival rates and the causes of death in a systemic sclerosis (SSc)
population, and to evaluate the occurrence of fatal malignant neoplasms and their possible …

Capillaroscopy is a non-invasive and safe tool which allows the evaluation of the morphology
of the microcirculation. Since its recent incorporation in the 2013 American College of …

Vasoconstriction accompanied by changes in skin color is a normal physiologic response to
cold. The distinction between this normal physiology and Raynaud's phenomenon (RP) has …

The aim of this study was to determine, through a genome-wide association study (GWAS),
the genetic components contributing to different clinical sub-phenotypes of systemic sclerosis …

Background Systemic sclerosis (SSc) is an autoimmune disease where controversy on Th1/Th2
balance dominates. We investigated whether the recently discovered Th17 pattern was …

In this study, 1,833 systemic sclerosis (SSc) cases and 3,466 controls were genotyped with
the Immunochip array. Classical alleles, amino acid residues, and SNPs across the human …

Objectives. To study the frequency and specificity of antinuclear antibodies (ANA) and their
association with internal organ involvement and survival in systemic sclerosis (SSc). Methods…