Background Patients with shift-work sleep disorder chronically have excessive sleepiness
during night work and insomnia when attempting to sleep during the day. We evaluated the …

Endogenous circadian clocks are robust regulators of physiology and behavior. Synchronization
or entrainment of biological clocks to environmental time is adaptive and important for …

Sleep, circadian rhythm, and neurobehavioral performance measures were obtained in five
astronauts before, during, and after 16-day or 10-day space missions. In space, scheduled …

Our aim was to explore the patient's perspective of outcomes in rheumatoid arthritis (RA) to
identify which outcomes are important to patients and how patients calibrate what constitutes …

Shift workers and transmeridian travelers are exposed to abnormal work-rest cycles, inducing
a change in the phase relationship between the sleep-wake cycle and the endogenous …

The Patient Perspective Workshop at OMERACT 7 addressed the question of assessing the
outcomes of intervention in rheumatoid arthritis (RA) from the perspective of those who …

Patient or consumer involvement in research is widely recommended, but although guidelines
for researchers and patients have been produced, few practical experiences have been …

The present investigation used a placebo-controlled, double-blind, crossover design to assess
the sleep-promoting effect of three melatonin replacement delivery strategies in a group …

Sleep—wake homeostatic and internal circadian timedependent brain processes interact to
regulate human brain function so that alert wakefulness is promoted during the daytime and …

The objective of the Patient Perspective Workshop at OMERACT 6 was to address the
question of assessing the outcomes of intervention in rheumatoid arthritis (RA) from the …