Background Asthma exacerbations are frequent in patients with severe disease. This report
describes results from two retrospective cohort studies describing exacerbation frequency …

Background Clinical and economic burden of patients with severe uncontrolled asthma (SUA)
in a real-world managed-care setting required further documentation. Objective The …

Objectives: Severe asthma comprises several distinct phenotypes. Consequently, patients
with severe asthma can be eligible for more than one biologic treatment targeting Th2 …

Background Severe uncontrolled asthma (SUA) is associated with increased asthma
exacerbations. Whether high blood eosinophil counts are related to this burden is uncertain. …

Background Data on the risk of death following an asthma exacerbation are scarce. With this
multinational cohort study, we assessed all-cause mortality rates, mortality rates following …

Objective. To assess the prevalence of chronic opioid use in patients with ankylosing spondylitis
(AS), and to compare the characteristics of patients with and without chronic opioid use. …

A nested case-control study was conducted to examine the association between host
immune status, as characterized by serum immune marker levels, and the development of …

Background Asthma is the most common chronic disease in childhood and places a significant
burden on public and private health systems. This retrospective cohort analysis utilised …

Objectives We examined the potential association between prior chronic obstructive pulmonary
disease (COPD) and edentulism, and whether the association varied by COPD severity …

Rationale. Asthma exacerbations are influenced by multiple factors including environmental
exposures, psychosocial interactions, and genetic variations. Aim. To better understand the …