The pathogenesis of inflammatory bowel disease (IBD) is multifactorial with data suggesting
the role of a disturbed interaction between the gut and the intestinal microbiota. A defective …

BACKGROUND: Ulcerative colitis and Crohn's disease are characterized by a chronic intestinal
inflammation. Since the precise etiology is still unknown, current therapies are aimed at …

We undertook a meta-analysis of six Crohn's disease genome-wide association studies (GWAS)
comprising 6,333 affected individuals (cases) and 15,056 controls and followed up the …

The cost of caring for patients with inflammatory bowel disease (IBD) continues to increase
worldwide. The cause is not only a steady increase in the prevalence of Crohn's disease and …

Objective The incidence of inflammatory bowel disease (IBD) is increasing in Eastern Europe.
The reasons for these changes remain unknown. The aim of this study was to investigate …

BACKGROUND & AIMS: Few data are available on effects of biologic therapies in patients
more than 65 years old with inflammatory bowel disease (IBD). We evaluated the risk and …

Background and aims Calprotectin and lactoferrin are specific neutrophil-derived proteins,
which can be measured in the feces because they are released by cells in inflammatory …

OBJECTIVE Assessing the clinical course of inflammatory bowel disease (IBD) patients
consists of periodical clinical evaluations and laboratory tests. We aimed to assess the role of …

OBJECTIVE: The clinical course of Crohn’s disease is often unpredictable. The aim of this
study was to select the most useful parameters able to predict clinical relapses. METHODS: …

Objectives Small intestinal permeability is often increased in patients with Crohn’s disease
and may be pathogenic for clinical relapses. No effective prophylactic treatment is available …