Multiple interacting checkpoints are involved in the pathophysiology of gout. Hyperuricemia
is the key risk factor for gout and is considered a prerequisite for monosodium urate (MSU) …

Objective The aim of this study was to examine whether serum urate-associated genetic
variants are associated with early-onset gout. Methods Participants with gout in the Genetics of …

Background Reduced renal clearance of uric acid is a major contributor to hyperuricemia.
The aim of this study was to examine clinical and genetic variables associated with fractional …

Background Sex-specific differences in the effect of genetic variants on serum urate levels
have been described. The aim of this study was to systematically examine whether serum …

Rationale & Objective The association between hyperuricemia and urolithiasis has been
previously reported. However, this association is based on observational data, which are prone …

Objective To examine whether urate‐associated genetic variants differ in their influence on
gout risk according to body mass index (BMI). Methods This research was conducted using …

Purpose This study aims to develop a model for predicting vitamin D deficiency in New Zealand
adults using easily accessible clinical characteristics. Methods Data were derived from …

Increasing therapeutic options are available for gout management. Anti-inflammatory agents
are used in the acute management of gout flares, and interleukin-1 inhibitors are effective …

Objective The aim of this study was to determine whether serum urate (SU)–associated genetic
variants differ in their influence on gout risk in people taking a diuretic compared to those …

A 56-year-old man was referred with left-sided hip pain. MRI scans demonstrated an undisplaced
stress fracture in the femoral neck and subchondral oedema within the femoral head. …