User profiles for R. de JONGE

Robert de Jonge

Professor and Chair
Verified email at vumc.nl
Cited by 9876

Improving food safety in the domestic environment: The need for a transdisciplinary approach

ARH Fischer, AEI De Jong, R De Jonge… - Risk Analysis: An …, 2005 - Wiley Online Library
Microbial food safety has been the focus of research across various disciplines within the
risk analysis community. Natural scientists involved in food microbiology and related …

Distinct and specific functions of cGMP-dependent protein kinases

…, A Smolenski, U Walter, HR De Jonge - Trends in biochemical …, 1997 - cell.com
cGMP-dependent protein kinases I and II conduct signals from widespread signaling systems.
Whereas the type I kinase mediates numerous effects of natriuretic peptides and nitric …

[HTML][HTML] Human enteroids/colonoids and intestinal organoids functionally recapitulate normal intestinal physiology and pathophysiology

…, J Foulke-Abel, J In, SE Blutt, HR De Jonge… - Journal of Biological …, 2016 - ASBMB
Identification of Lgr5 as the intestinal stem cell marker as well as the growth factors necessary
to replicate adult intestinal stem cell division has led to the establishment of the methods to …

Relationship between genetic variants in the adenosine pathway and outcome of methotrexate treatment in patients with recent‐onset rheumatoid arthritis

JAM Wessels, WM Kooloos, RD Jonge… - Arthritis & …, 2006 - Wiley Online Library
Objective Among patients with rheumatoid arthritis (RA), there is a high degree of interindividual
variability in the degree of response to methotrexate (MTX) treatment. This study was …

A functional CFTR assay using primary cystic fibrosis intestinal organoids

JF Dekkers, CL Wiegerinck, HR De Jonge… - Nature medicine, 2013 - nature.com
We recently established conditions allowing for long-term expansion of epithelial organoids
from intestine, recapitulating essential features of the in vivo tissue architecture. Here we …

Future challenges to microbial food safety

AH Havelaar, S Brul, A De Jong, R De Jonge… - International Journal of …, 2010 - Elsevier
Despite significant efforts by all parties involved, there is still a considerable burden of
foodborne illness, in which micro-organisms play a prominent role. Microbes can enter the food …

Cross‐contamination in the kitchen: effect of hygiene measures

…, MJ Nauta, R De Jonge - Journal of Applied …, 2008 - academic.oup.com
Aims: To determine the effect of hygiene measures on cross‐contamination of Campylobacter
jejuni at home and to select a safe tracer organism for C. jejuni. Methods and Results: …

Cross‐contamination in the kitchen: estimation of transfer rates for cutting boards, hands and knives

…, AEI De Jong, R De Jonge… - Journal of applied …, 2008 - academic.oup.com
… Methods and Results: Based on laboratory scenarios performed by de Jong et al. (2008)
, transfer rates were estimated for Campylobacter jejuni and Lactobacillus casei as a tracer …

Resveratrol provides late-phase cardioprotection by means of a nitric oxide-and adenosine-mediated mechanism

…, R De Jonge, P Beemster, JW De Jong - European journal of …, 2003 - Elsevier
We used two experimental models to prove that resveratrol (trans-3,4′,5-trihydroxystilbene)
reduces cardiac ischemic-reperfusion injury by means of a nitric oxide- and adenosine-…

Food safety in the domestic environment: an interdisciplinary investigation of microbial hazards during food preparation

…, ED Van Asselt, R De Jonge… - Risk Analysis: An …, 2007 - Wiley Online Library
… Contamination levels of salads were determined as described by De Jong (submitted) by
use of the most-probable number (MPN) method (triplicate tubes per dilution) in combination …