Amyloidosis is a protein misfolding disorder in which soluble proteins aggregate as insoluble
amyloid fibrils. Protein aggregates and amyloid fibrils cause functional and structural organ …

Although it has been known for long time that atherosclerosis is associated with lipid
deposition, only recently it has been accepted that the plasmatic concentration of cholesterol, …

Endothelial progenitor cell (EPC) mobilization has been reported following tissue damage,
whereas no data are available regarding the mobilization of hematopoietic progenitor cells (…

Background— Brain natriuretic peptide (BNP) is a marker of ventricular dysfunction and can
be used to assess prognosis in heart failure and after myocardial infarction. Heart …

Aims Anaemia is often observed in patients with chronic heart failure (CHF), and it may be
associated with a worse prognosis. Aim of this study was to identify the individual mechanisms …

The kidney is involved in 70% of patients with immunoglobulin light-chain (AL) amyloidosis,
but little is known on progression or reversibility of renal involvement, and criteria for renal …

N-terminal natriuretic peptide type B (NT-proBNP) is a marker of cardiac dysfunction in light
chain amyloidosis (AL) and a powerful prognostic determinant. Serum NT-proBNP and …

Background: The diagnosis of systemic immunoglobulin light-chain (AL) amyloidosis requires
demonstration of amyloid deposits in a tissue biopsy and amyloidogenic monoclonal light …

… ), the shrinkage coefficient for calibration (measuring the accuracy of the model, ie, the
agreement between observed outcome and prediction), and the Royston explained variation (R 2 …

Background A large amount of evidence suggests a possible role of interleukin-6 (IL-6) in the
pathogenesis of hepatocellular carcinoma (HCC). Patients and methods We studied both IL…