Sindbis viruses and other alphaviruses as cause of human arthritic disease

M Laine, R Luukkainen… - Journal of internal …, 2004 - Wiley Online Library
Amongst the arthritis‐causing arboviruses, ie those spread by insects, the alphavirus group
is of special interest. These viruses occasionally cause vast outbreaks, such as O'nyong‐…

Comparison of combination therapy with single-drug therapy in early rheumatoid arthritis: a randomised trial

…, M Korpela, L Laasonen, H Julkunen, R Luukkainen… - The Lancet, 1999 - thelancet.com
Background The treatment of rheumatoid arthritis should aim at clinical remission. This
multicentre, randomised trial with 2-year follow-up sought evidence on the efficacy and tolerability …

[HTML][HTML] Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study

…, K Hørslev-Petersen, RK Luukkainen… - Arthritis research & …, 2008 - Springer
Introduction We analyzed the prevalence of cardiovascular (CV) disease in patients with
rheumatoid arthritis (RA) and its association with traditional CV risk factors, clinical features of …

CD4+ CD25+ T cells with the phenotypic and functional characteristics of regulatory T cells are enriched in the synovial fluid of patients with rheumatoid arthritis

…, L Mustonen, P Isomäki, R Luukkainen… - Clinical & …, 2005 - academic.oup.com
CD4 + CD25 + regulatory T (T reg ) cells play a critical role in the maintenance of peripheral
tolerance and the prevention of autoimmunity. In the present study, we have explored the …

Fecal microbiota in early rheumatoid arthritis

…, E Munukka, M Korkeamäki, R Luukkainen… - The Journal of …, 2008 - jrheum.org
… The result was calculated with the R package. In all analyses, ap value ≤ 0.05 was …
Hopkins MJ, Sharp R, Macfarlane GT. Age and disease related changes in intestinal bacterial …

[HTML][HTML] Work disability remains a major problem in rheumatoid arthritis in the 2000s: data from 32 countries in the QUEST-RA study

…, IMM Laurindo, J Lazovskis, R Luukkainen… - Arthritis research & …, 2010 - Springer
Introduction Work disability is a major consequence of rheumatoid arthritis (RA), associated
not only with traditional disease activity variables, but also more significantly with …

Isolation and characterization of a variety of microcystins from seven strains of the cyanobacterial genus Anabaena

…, F Sun, L Rouhiainen, R Luukkainen… - Applied and …, 1992 - Am Soc Microbiol
Hepatotoxins (microcystins) from seven freshwater Anabaena strains originating from three
different Finnish lakes and one lake in Norway were isolated by high-performance liquid …

Anatoxin-a concentration inAnabaena andAphanizomenon under different environmental conditions and comparison of growth by toxic and non-toxicAnabaena …

J Rapala, K Sivonen, R Luukkainen… - Journal of applied …, 1993 - Springer
Anatoxin-a-concentration in cells ofAnabaena- andAphanizomenon-strains and in their
growth media were studied in the laboratory in batch cultures at different temperatures, light …

Remission and rheumatoid arthritis: data on patients receiving usual care in twenty‐four countries

…, K Hørslev‐Petersen, RK Luukkainen… - Arthritis & …, 2008 - Wiley Online Library
Objective To compare the performance of different definitions of remission in a large
multinational cross‐sectional cohort of patients with rheumatoid arthritis (RA). Methods The …

Periarticular corticosteroid treatment of the sacroiliac joint in patients with seronegative spondylarthropathy.

R Luukkainen, M Nissilä, E Asikainen… - Clinical and …, 1999 - europepmc.org
Objective To evaluate the efficacy of periarticular corticosteroid injection of the sacroiliac joint
(SIJ) in patients with seronegative spondylarthropathy in a double blind, controlled study. …