Spatial planning of public charging points using multi-dimensional analysis of early adopters of electric vehicles for a city region
The success of a mass roll out of Plug-in electric vehicles (PEVs) is largely underpinned by
establishment of suitable charging infrastructure. This paper presents a geospatial modelling …
establishment of suitable charging infrastructure. This paper presents a geospatial modelling …
Macrophage migration inhibitory factor counterregulates dexamethasone-mediated suppression of hypoxia-inducible factor-1α function and differentially influences …
…, M Wagegg, C Stahn, P Kolar, R Dziurla… - The Journal of …, 2011 - journals.aai.org
Hypoxia, a feature of inflammation and tumors, is a potent inducer of the proinflammatory
cytokine macrophage migration inhibitory factor (MIF). In transformed cells, MIF was shown to …
cytokine macrophage migration inhibitory factor (MIF). In transformed cells, MIF was shown to …
Human CD4+ T cells maintain specific functions even under conditions of extremely restricted ATP production
R Tripmacher, T Gaber, R Dziurla… - European journal of …, 2008 - Wiley Online Library
We investigated the energy‐adaptive potential of human CD4 + T cells under conditions of
impaired oxidative phosphorylation (OXPHOS) and/or low glucose (inhibiting glycolysis). …
impaired oxidative phosphorylation (OXPHOS) and/or low glucose (inhibiting glycolysis). …
Human immune cells' behavior and survival under bioenergetically restricted conditions in an in vitro fracture hematoma model
…, T Raue, K Schmidt-Bleek, R Dziurla… - Cellular & molecular …, 2013 - nature.com
The initial inflammatory phase of bone fracture healing represents a critical step for the
outcome of the healing process. However, both the mechanisms initiating this inflammatory …
outcome of the healing process. However, both the mechanisms initiating this inflammatory …
Effects of hypoxia and/or lack of glucose on cellular energy metabolism and cytokine production in stimulated human CD4+ T lymphocytes
R Dziurla, T Gaber, M Fangradt, M Hahne… - Immunology letters, 2010 - Elsevier
Oxidative phosphorylation and/or glycolysis provide energy, mainly in the form of ATP, which
ensures proper functioning of immune cells such as CD4 + T lymphocytes. However, the …
ensures proper functioning of immune cells such as CD4 + T lymphocytes. However, the …
Adaptation of human CD4+ T cells to pathophysiological hypoxia: a transcriptome analysis
…, M Tschirschmann, M Hahne, R Dziurla… - The Journal of …, 2009 - jrheum.org
Objective. Inflamed tissues are usually characterized by low oxygen levels. We investigated
whether pathophysiological hypoxia (pO 2 < 1%) as found in the rheumatoid synovium …
whether pathophysiological hypoxia (pO 2 < 1%) as found in the rheumatoid synovium …
Hypoxia inducible factor (HIF) in rheumatology: low O2! See what HIF can do!
T Gaber, R Dziurla, R Tripmacher… - Annals of the …, 2005 - ard.bmj.com
Maintenance of oxygen homoeostasis is the basic principle in cell proliferation,
differentiation, survival, and function in all higher organisms. The transcription factor, HIF (hypoxia …
differentiation, survival, and function in all higher organisms. The transcription factor, HIF (hypoxia …
[PDF][PDF] Effects of treatment with etanercept versus methotrexate on sleep quality, fatigue and selected immune parameters in patients with active rheumatoid arthritis
J Detert, R Dziurla, P Hoff, T Gaber, P Klaus… - Clin Exp …, 2016 - clinexprheumatol.org
… SCHWARZ R, KRAUSS O, HINZ A: Fatigue in the general population. Onkologie 2003: 26:
140-4. … STAUD R: Peripheral and central mechanisms of fatigue in inflammatory and …
140-4. … STAUD R: Peripheral and central mechanisms of fatigue in inflammatory and …
Inflammation is an important covariate for the crosstalk of sleep and the HPA axis in rheumatoid arthritis
RH Straub, J Detert, R Dziurla, I Fietze… - …, 2017 - karger.com
Rheumatoid arthritis (RA) patients have sleep problems, and inflammation influences sleep.
We demonstrated that sleep quality improves during intensified treatment with methotrexate (…
We demonstrated that sleep quality improves during intensified treatment with methotrexate (…
[PDF][PDF] Effects of celecoxib on the expression of osteoprotegerin, energy metabolism and cell viability in cultured human osteoblastic cells
…, R Dziurla, R Tripmacher… - Clinical & …, 2009 - clinexprheumatol.org
Methods Primary human osteoblasts and MG-63 cells were incubated with celecoxib (2, 10,
50μM). Cell viability and apoptosis were determined by trypan blue, 7AAD and Annexin-V …
50μM). Cell viability and apoptosis were determined by trypan blue, 7AAD and Annexin-V …