The immunomodulatory effects of estrogens: clinical relevance in immune‐mediated rheumatic diseases

M Cutolo, R Brizzolara, F Atzeni… - Annals of the New …, 2010 - Wiley Online Library
Immunological, epidemiological, and clinical evidence suggest that female sex hormones
play an important role in the etiology and pathophysiology of chronic immune/inflammatory …

On the electrochemical etching of tips for scanning tunneling microscopy

JP Ibe, PP Bey Jr, SL Brandow, RA Brizzolara… - Journal of Vacuum …, 1990 - pubs.aip.org
The sharpness of tips used in scanning tunneling microscopy (STM) is one factor which
affects the resolution of the STM image. In this paper, we report on a direct‐current (dc) drop‐off …

Regulation of apoptosis in endocrine autoimmunity: insights from Hashimoto's thyroiditis and Graves' disease

…, G Pesce, P Montagna, R Brizzolara… - Annals of the New …, 2002 - Wiley Online Library
Dysregulation of apoptosis is associated with the pathogenesis of organ‐specific autoimmune
diseases, through altered target organ susceptibility. Apoptosis signaling pathways can …

[HTML][HTML] A circulating cell population showing both M1 and M2 monocyte/macrophage surface markers characterizes systemic sclerosis patients with lung involvement

…, V Tomatis, B Ruaro, S Paolino, R Brizzolara… - Respiratory …, 2018 - Springer
Background Systemic sclerosis (SSc) is a disorder characterized by immune system
alterations, vasculopathy and fibrosis. SSc-related interstitial lung disease (ILD) represents a …

Sonication of bacteria, phytoplankton and zooplankton: application to treatment of ballast water

ER Holm, DM Stamper, RA Brizzolara, L Barnes… - Marine Pollution …, 2008 - Elsevier
We investigated the effect of high power ultrasound, at a frequency of 19kHz, on the survival
of bacteria, phytoplankton and zooplankton, in order to obtain estimates of effective …

Soluble CTLA-4 in autoimmune thyroid diseases: relationship with clinical status and possible role in the immune response dysregulation

D Saverino, R Brizzolara, R Simone, A Chiappori… - Clinical …, 2007 - Elsevier
CTLA-4 molecule, expressed by activated T and B lymphocytes, transduces an inhibitory
signal. Increasing evidence showed CTLA-4 gene as an important susceptibility locus for …

Increase in circulating cells coexpressing M1 and M2 macrophage surface markers in patients with systemic sclerosis

…, P Contini, V Tomatis, B Ruaro, R Brizzolara… - Annals of the …, 2018 - ard.bmj.com
An M2 pre-eminent phenotype has been postulated for SSc monocytes/macrophages. 2 The
aim of the study was to widen a phenotype characterisation (M1, M2 and mixed M1/M2) of …

[HTML][HTML] CTLA4-Ig interacts with cultured synovial macrophages from rheumatoid arthritis patients and downregulates cytokine production

…, P Triolo, P Clerico, L Felli, R Brizzolara - Arthritis research & …, 2009 - Springer
Introduction Co-stimulatory signal B7(CD80/CD86):CD28 is needed in order to activate T
cells in immune response. Cytotoxic T lymphocyte-associated antigen-4-immunoglobulin (…

Raynaud's phenomenon and plasma endothelin: correlations with capillaroscopic patterns in systemic sclerosis

…, B Villaggio, B Seriolo, R Brizzolara… - The Journal of …, 2009 - jrheum.org
Objective. We evaluated endothelin (ET)-1 plasma levels and some clinical measures in
patients with primary Raynaud’s phenomenon (PRP), and in patients with systemic sclerosis (…

[HTML][HTML] Alternatively activated (M2) macrophage phenotype is inducible by endothelin-1 in cultured human macrophages

…, S Paolino, AC Trombetta, P Montagna, R Brizzolara… - PLoS …, 2016 - journals.plos.org
Background Alternatively activated (M2) macrophages are phenotypically characterized by
the expression of specific markers, mainly macrophage scavenger receptors (CD204 and …