The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis …

…, S Keeling, J Dutz, L Bessette, R Bissonnette… - Annals of the …, 2015 - ard.bmj.com
The objective of this systematic literature review was to determine the association between
cardiovascular events (CVEs) and antirheumatic drugs in rheumatoid arthritis (RA) and …

The end of the (cell) line: methods for the study of apoptosis in vitro

AJ McGahon, SJ Martin, RP Bissonnette… - Methods in cell …, 1995 - Elsevier
Publisher Summary This chapter describes techniques commonly used to study cell death
using in vitro cell culture systems. These techniques include a range of simple dye exclusion …

Daylight photodynamic therapy for actinic keratosis: an international consensus: International Society for Photodynamic Therapy in Dermatology

…, N Basset‐Seguin, R Bissonnette… - Journal of the …, 2012 - Wiley Online Library
Photodynamic therapy (PDT) is an attractive therapy for non‐melanoma skin cancers including
actinic keratoses (AKs) because it allows treatment of large areas; it has a high response …

Apoptotic cell death induced by c-myc is inhibited by bcl-2

RP Bissonnette, F Echeverri, A Mahboubi, DR Green - Nature, 1992 - nature.com
APOPTOSIS is a form of physiological cell death, characterized by chromatin condensation,
cytoplasmic blebbing and DNA fragmentation 1 , which often depends on RNA and protein …

Guidelines on the use of photodynamic therapy for nonmelanoma skin cancer: an international consensus

…, R Bissonnette, P Foley, D Pariser, R Roelandts… - Journal of the American …, 2007 - Elsevier
Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as
actinic keratoses, Bowen's disease, and basal cell carcinoma (superficial and nodular). This …

Role for c-myc in activation-induced apoptotic cell death in T cell hybridomas

Y Shi, JM Glynn, LJ Guilbert, TG Cotter, RP Bissonnette… - Science, 1992 - science.org
Immature T cells and some T cell hybridomas undergo apoptotic cell death when activated
through the T cell receptor complex, a phenomenon that is probably related to antigen …

Baricitinib in patients with moderate‐to‐severe atopic dermatitis and inadequate response to topical corticosteroids: results from two randomized monotherapy phase …

…, LF Eichenfield, R Bissonnette… - British Journal of …, 2020 - academic.oup.com
Background Baricitinib, an oral selective Janus kinase 1 and 2 inhibitor, effectively reduced
atopic dermatitis (AD) severity in a phase II study with concomitant topical corticosteroids. …

Topical tofacitinib for atopic dermatitis: a phase IIa randomized trial

R Bissonnette, KA Papp, Y Poulin… - British Journal of …, 2016 - academic.oup.com
Background Despite unmet need, 15 years have passed since a topical therapy with a new
mechanism of action for atopic dermatitis (AD) has been approved. Janus kinase (JAK) …

BCR-ABL maintains resistance of chronic myelogenous leukemia cells to apoptotic cell death [published erratum appears in Blood 1994 Jun 15; 83 (12): 3835]

A McGahon, R Bissonnette, M Schmitt, KM Cotter… - 1994 - ashpublications.org
Apoptosis is the major form of cell death associated with the action of chemotherapeutic
agents on tumor cells, and therefore the expression of genes that interfere with apoptosis can …

[HTML][HTML] Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis

E Guttman-Yassky, R Bissonnette, B Ungar… - Journal of Allergy and …, 2019 - Elsevier
Background Dupilumab is an IL-4 receptor α mAb inhibiting signaling of IL-4 and IL-13, key
drivers of type 2–driven inflammation, as demonstrated by its efficacy in patients with atopic/…