The structure of the octameric histone core of the nucleosome has been determined by x-ray
crystallography to a resolution of 3.1 A. The histone octamer is a tripartite assembly in which …

To gain insight into the mechanisms of autoantibody induction, sera from 40 patients with
systemic lupus erythematosus (SLE) were tested by ELISAs for antibody binding to denatured …

Susceptibility to systemic lupus erythematosus has been unequivocally established to be an
inherited trait, but the exact genes and how they confer susceptibility remain largely …

C-Reactive protein (CRP) is an acute phase serum protein in man that binds to certain
bacterial polysaccharides and to components exposed on damaged cells. CRP is bound by …

Objective. Autoantibodies are important in the diagnosis and classification of systemic lupus
erythematosus (SLE), but whether they correlate with changes in disease activity within …

Emerging evidence suggests that there are IgM-autoantibodies that may play protective
roles in SLE. While IgM are often considered polyreactive, we postulate that there are distinct …

The term ‘cocaine‐induced pseudovasculitis' was coined to encompass a constellation of
clinical and laboratory findings which mimics a systemic vasculitis but lacks confirmatory …

Anti-chromatin (nucleosome) autoantibodies were one of the first autoantibodies ever detected
since they make up the majority of antibodies causing LE Cell formation. The prevalence …

Background: Anti-chromatin antibodies have recently been described in patients with systemic
lupus erythematosus (SLE) and it has been suggested that their presence is associated …

… RW Burlingame, RL Rubin, RS Balderas, and AN Theofilopoulos … Bell, and RW Burlingame.
Autoantibodies associated with lupus induced by diverse drugs target a similar epitope in …