[HTML][HTML] Linkage of periodontitis and rheumatoid arthritis: current evidence and potential biological interactions

RS de Molon, C Rossa Jr, RM Thurlings… - International journal of …, 2019 - mdpi.com
The association between rheumatoid arthritis (RA) and periodontal disease (PD) has been
the focus of numerous investigations driven by their common pathological features. RA is an …

[HTML][HTML] Morphea and eosinophilic fasciitis: an update

JS Mertens, MMB Seyger, RM Thurlings… - American journal of …, 2017 - Springer
Morphea, also known as localized scleroderma, encompasses a group of idiopathic sclerotic
skin diseases. The spectrum ranges from relatively mild phenotypes, which generally …

Synovial tissue response to rituximab: mechanism of action and identification of biomarkers of response

RM Thurlings, K Vos, CA Wijbrandts… - Annals of the …, 2008 - ard.bmj.com
Objective: To investigate the synovial tissue in patients with rheumatoid arthritis (RA) treated
with rituximab and to identify possible predictors of clinical response. Methods: A total of 24 …

Atacicept in patients with rheumatoid arthritis: results of a multicenter, phase Ib, double‐blind, placebo‐controlled, dose‐escalating, single‐and repeated‐dose study

PP Tak, RM Thurlings, C Rossier… - Arthritis & …, 2008 - Wiley Online Library
Objective Atacicept is a recombinant fusion protein that binds and neutralizes B lymphocyte
stimulator and a proliferation‐inducing ligand. The purpose of this study was to investigate …

[HTML][HTML] Post-traumatic knee osteoarthritis; the role of inflammation and hemarthrosis on disease progression

…, PM van der Kraan, S Koëter, RM Thurlings - Frontiers in …, 2022 - frontiersin.org
Knee injuries such as anterior cruciate liamgent ruptures and meniscal injury are common
and are most frequently sustained by young and active individuals. Knee injuries will lead to …

Early effects of rituximab on the synovial cell infiltrate in patients with rheumatoid arthritis

K Vos, RM Thurlings, CA Wijbrandts… - Arthritis & …, 2007 - Wiley Online Library
Objective To study the specific effects of rituximab treatment on the synovium in patients with
rheumatoid arthritis (RA) early after initiation of treatment. Methods Seventeen RA patients …

MRP8/14 serum levels as a strong predictor of response to biological treatments in patients with rheumatoid arthritis

…, DM Gerlag, MJ Herenius, RM Thurlings… - Annals of the …, 2015 - ard.bmj.com
Background One-third of rheumatoid arthritis (RA) patients treated with biological therapy
show lack of response. The use of predictive biomarkers to identify responders to treatment …

Relationship between the type I interferon signature and the response to rituximab in rheumatoid arthritis patients

RM Thurlings, M Boumans, J Tekstra… - Arthritis & …, 2010 - Wiley Online Library
Relationship between the type I interferon signature and the response to rituximab in rheumatoid
arthritis patients - Thurlings - 2010 - Arthritis & Rheumatism - Wiley Online Library …

[HTML][HTML] Prevalence and pharmacological modulation of humoral immunity to AAV vectors in gene transfer to synovial tissue

…, Y Chen, SC Edmonson, S Zhou, RM Thurlings… - Gene therapy, 2013 - nature.com
Antibodies against adeno-associated viral (AAV) vectors are highly prevalent in humans.
Both preclinical and clinical studies showed that antibodies against AAV block transduction …

Synovial tissue sublining CD68 expression is a biomarker of therapeutic response in rheumatoid arthritis clinical trials: consistency across centers

B Bresnihan, E Pontifex, RM Thurlings… - The Journal of …, 2009 - jrheum.org
Objective. To determine whether the correlation between the mean change in disease activity
and the mean change in synovial sublining (sl) CD68 expression could be demonstrated …