User profiles for R. M. Pinto

Ricardo Mouro Pinto, PhD MSc

- Verified email at mgh.harvard.edu - Cited by 2363

Rute Maria Pinto

- Verified email at exseed.ed.ac.uk - Cited by 1350

Development, evaluation, and standardization of a real-time TaqMan reverse transcription-PCR assay for quantification of hepatitis A virus in clinical and shellfish …

MI Costafreda, A Bosch, RM Pintó - Applied and environmental …, 2006 - Am Soc Microbiol
A standardized real-time reverse transcription-PCR (RT-PCR) assay has been developed for
an accurate estimation of the number of genome copies of hepatitis A virus (HAV) in clinical …

Survival of enteric viruses on environmental fomites

FX Abad, RM Pinto, A Bosch - Applied and environmental …, 1994 - Am Soc Microbiol
The survival of human enteric viruses on several porous (paper and cotton cloth) and nonporous
(aluminum, china, glazed tile, latex, and polystyrene) environmental surfaces has been …

A prenylated dsRNA sensor protects against severe COVID-19

…, I Jarmson, N Cameron-Ruiz, M Varjak, RM Pinto… - Science, 2021 - science.org
INTRODUCTION Interferons (IFNs) are cytokines that are rapidly deployed in response to
invading pathogens. By initiating a signaling cascade that stimulates the expression of …

The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

…, G Yebra, S Shaaban, MTG Holden, RM Pinto… - MedRxiv, 2022 - medrxiv.org
Vaccination-based exposure to spike protein derived from early SARS-CoV-2 sequences is
the key public health strategy against COVID-19. Successive waves of SARS-CoV-2 …

Human astroviruses

A Bosch, RM Pintó, S Guix - Clinical microbiology reviews, 2014 - Am Soc Microbiol
Human astroviruses (HAtVs) are positive-sense single-stranded RNA viruses that were
discovered in 1975. Astroviruses infecting other species, particularly mammalian and avian, were …

[PDF][PDF] Identification of genetic factors that modify clinical onset of Huntington's disease

…, VC Wheeler, MJ Chao, JPG Vonsattel, RM Pinto… - Cell, 2015 - cell.com
As a Mendelian neurodegenerative disorder, the genetic risk of Huntington's disease (HD)
is conferred entirely by an HTT CAG repeat expansion whose length is the primary …

[HTML][HTML] SARS-CoV-2 Omicron is an immune escape variant with an altered cell entry pathway

…, G Yebra, S Shaaban, MTG Holden, RM Pinto… - Nature …, 2022 - nature.com
Vaccines based on the spike protein of SARS-CoV-2 are a cornerstone of the public health
response to COVID-19. The emergence of hypermutated, increasingly transmissible variants …

[HTML][HTML] In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2

…, A Merits, RJ Orton, OA MacLean, RM Pinto… - PLoS …, 2021 - journals.plos.org
Remdesivir (RDV), a broadly acting nucleoside analogue, is the only FDA approved small
molecule antiviral for the treatment of COVID-19 patients. To date, there are no reports …

[HTML][HTML] A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research

…, A Orr, RJ Orton, M Palmarini, YA Parr, RM Pinto… - PLoS …, 2021 - journals.plos.org
The recent emergence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2),
the underlying cause of Coronavirus Disease 2019 (COVID-19), has led to a worldwide …

Outcome of children with acute leukemia given HLA-haploidentical HSCT after αβ T-cell and B-cell depletion

…, V Bertaina, M Algeri, RM Pinto… - Blood, The Journal …, 2017 - ashpublications.org
Allogeneic hematopoietic stem cell transplantation (HSCT) from an HLA-haploidentical relative
(haplo-HSCT) is a suitable option for children with acute leukemia (AL) either relapsed or …