Nitric oxide provokes vasodilation and inhibits platelet aggregation. We examined the effect
of nitric oxide on superoxide anion production by three sources: activated intact neutrophils, …

Objective: Nitric oxide, a potent vasodilator released by endothelial cells, inhibits platelet
aggregation and adhesion to vascular endothelial surfaces. Because endothelial cell damage …

Recent research has recognised new populations of non-hematopoïetic cells in the blood.
One of these, circulating endothelial cells (CECs), often defined by the expression of …

Antibodies to DNA and chromatin drive autoimmunity in systemic lupus erythematosus (SLE).
Null mutations and hypomorphic variants of the secreted deoxyribonuclease DNASE1L3 …

Nitric oxide (NO), first identified as an endothelium-derived relaxation factor, is now
recognized to regulate the functions of many mammalian cells and tissues. Nitric oxide is …

We performed experiments to determine whether nitric oxide promoted the formation of
intracellular S-nitrosothiol adducts in human neutrophils. At concentrations sufficient to inhibit …

Objective To evaluate seroreactivity and disease flares after COVID‐19 vaccination in a
multiethnic/multiracial cohort of patients with systemic lupus erythematosus (SLE). Methods …

Nitric oxide (NO) is synthesized via the oxidation of arginine by a family of nitric oxide synthases
(NOS), which are either constitutive (ie. endothelial (ec)NOS and neuronal (nc)NOS) or …

Objective. Identifying the frequency of recurrent cardiac manifestations of neonatal lupus (NL)
in a second child is critical to understanding the pathogenesis of anti-SSA/Ro–mediated …

Despite the near universal association of congenital heart block and maternal Abs to SSA/Ro
and SSB/La, the intracellular location of these Ags has made it difficult to substantiate their …