Bupropion: pharmacology and therapeutic applications
KF Foley, KP DeSanty, RE Kast - Expert review of …, 2006 - Taylor & Francis
… Despite these last two trials, most trials with bupropion have shown it to be moderately
effective as an aid to smoking cessation. Interestingly, a history of depression is not a factor in the …
effective as an aid to smoking cessation. Interestingly, a history of depression is not a factor in the …
[HTML][HTML] A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the …
RE Kast, JA Boockvar, A Brüning, F Cappello… - Oncotarget, 2013 - ncbi.nlm.nih.gov
… Sertraline is a 306 Da selective serotonin re-uptake inhibitor (SSRI) in common use over the
last twenty years in the treatment of depressed mood [203]. It is usually well-tolerated and is …
last twenty years in the treatment of depressed mood [203]. It is usually well-tolerated and is …
Emerging technology: applications of Raman spectroscopy for prostate cancer
There is a need in prostate cancer diagnostics and research for a label-free imaging
methodology that is nondestructive, rapid, objective, and uninfluenced by water. Raman …
methodology that is nondestructive, rapid, objective, and uninfluenced by water. Raman …
A new chapter opens in anti-inflammatory treatments: the antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice
D Brustolim, R Ribeiro-dos-Santos, RE Kast… - International …, 2006 - Elsevier
In a wide range of human diseases of inflammatory nature like Crohn's disease, pathology
is mediated in part by pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF) or …
is mediated in part by pro-inflammatory cytokines like tumor necrosis factor-alpha (TNF) or …
Raman spectroscopy to distinguish grey matter, necrosis, and glioblastoma multiforme in frozen tissue sections
SN Kalkanis, RE Kast, ML Rosenblum… - Journal of neuro …, 2014 - Springer
The need exists for a highly accurate, efficient and inexpensive tool to distinguish normal
brain tissue from glioblastoma multiforme (GBM) and necrosis boundaries rapidly, in real-time, …
brain tissue from glioblastoma multiforme (GBM) and necrosis boundaries rapidly, in real-time, …
[HTML][HTML] Disulfiram, a drug widely used to control alcoholism, suppresses self-renewal of glioblastoma and overrides resistance to temozolomide
…, K Hu, A Fotovati, R Berns, M Pambid, M Luk, RE Kast… - Oncotarget, 2012 - ncbi.nlm.nih.gov
… Tumor re-growth and relapse is a major problem in treating GBM. A growing body of
genetic analysis of GBM suggests that cell cycle and regulatory factors are key drivers of the …
genetic analysis of GBM suggests that cell cycle and regulatory factors are key drivers of the …
Cancer chemotherapy and cachexia: Mirtazapine and olanzapine are 5‐HT3 antagonists with good antinausea effects
RE Kast, KF Foley - European journal of cancer care, 2007 - Wiley Online Library
Mirtazapine and olanzapine are easy‐to‐use psychiatric drugs with potent antinausea effects.
Ondansetron and later members of the ’setron class are currently standard treatments for …
Ondansetron and later members of the ’setron class are currently standard treatments for …
[HTML][HTML] CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline …
RE Kast, G Karpel-Massler, ME Halatsch - Oncotarget, 2014 - ncbi.nlm.nih.gov
… To develop CUSP9 we found nine re-positioned (re-purposed), already-marketed drugs
that had evidence supporting their ability to inhibit one or more of the identified glioblastoma …
that had evidence supporting their ability to inhibit one or more of the identified glioblastoma …
Raman spectroscopy can differentiate malignant tumors from normal breast tissue and detect early neoplastic changes in a mouse model
RE Kast, GK Serhatkulu, A Cao… - Biopolymers …, 2008 - Wiley Online Library
Raman spectroscopy shows potential in differentiating tumors from normal tissue. We used
Raman spectroscopy with near‐infrared light excitation to study normal breast tissue and …
Raman spectroscopy with near‐infrared light excitation to study normal breast tissue and …
Lithium and hematology: established and proposed uses
D Focosi, A Azzara, RE Kast, G Carulli… - Journal of Leucocyte …, 2009 - academic.oup.com
Lithium (as lithium carbonate) is an unexpensive drug, widely used in psychiatry for over 50
years in treatment of mood instability (bipolar disorder) and as an adjunct to antidepressants…
years in treatment of mood instability (bipolar disorder) and as an adjunct to antidepressants…