Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
…, D Smailus, M Moksa, Y Zhao, A Delaney, H Qian… - Nature …, 2010 - nature.com
Follicular lymphoma (FL) and the GCB subtype of diffuse large B-cell lymphoma (DLBCL)
derive from germinal center B cells 1 . Targeted resequencing studies have revealed …
derive from germinal center B cells 1 . Targeted resequencing studies have revealed …
[PDF][PDF] Single particle tracking. Analysis of diffusion and flow in two-dimensional systems
Analysis of the trajectories of small particles at high spatial and temporal resolution using
video enhanced contrast microscopy provides a powerful approach to characterizing the …
video enhanced contrast microscopy provides a powerful approach to characterizing the …
Macrophages regulate the angiogenic switch in a mouse model of breast cancer
…, L Gnatovskiy, Y Deng, L Zhu, DA Grzesik, H Qian… - Cancer research, 2006 - AACR
The development of a tumor vasculature or access to the host vasculature is a crucial step for
the survival and metastasis of malignant tumors. Although therapeutic strategies attempting …
the survival and metastasis of malignant tumors. Although therapeutic strategies attempting …
V. PhyloMaker: an R package that can generate very large phylogenies for vascular plants
Y Jin, H Qian - Ecography, 2019 - Wiley Online Library
We present V.PhyloMaker, a freely available package for R designed to generate
phylogenies for vascular plants. The mega‐tree implemented in V.PhyloMaker (ie GBOTB.extended.tre)…
phylogenies for vascular plants. The mega‐tree implemented in V.PhyloMaker (ie GBOTB.extended.tre)…
[PDF][PDF] Critical role of thrombopoietin in maintaining adult quiescent hematopoietic stem cells
The role of cytokines in regulation of hematopoietic stem cells (HSCs) remains poorly
understood. Herein we demonstrate that thrombopoietin (THPO) and its receptor, MPL, are …
understood. Herein we demonstrate that thrombopoietin (THPO) and its receptor, MPL, are …
Large-scale processes and the Asian bias in species diversity of temperate plants
H Qian, RE Ricklefs - Nature, 2000 - nature.com
An important issue in the study of biodiversity is the extent to which global patterns of
species richness reflect large-scale processes and historical contingencies 1 , 2 . Ecological …
species richness reflect large-scale processes and historical contingencies 1 , 2 . Ecological …
Parameters of helix–coil transition theory for alanine‐based peptides of varying chain lengths in water
JM Scholtz, H Qian, EJ York, JM Stewart… - Biopolymers …, 1991 - Wiley Online Library
Thermal unfolding curves have been measured for a series of short alanine‐based peptides
that contain repeating sequences and varying chain lengths. Standard helix–coil theory …
that contain repeating sequences and varying chain lengths. Standard helix–coil theory …
Phosphorylation energy hypothesis: open chemical systems and their biological functions
H Qian - Annu. Rev. Phys. Chem., 2007 - annualreviews.org
Biochemical systems and processes in living cells generally operate far from equilibrium.
This review presents an overview of a statistical thermodynamic treatment for such systems, …
This review presents an overview of a statistical thermodynamic treatment for such systems, …
Black-box tuning for language-model-as-a-service
Extremely large pre-trained language models (PTMs) such as GPT-3 are usually released
as a service. It allows users to design task-specific prompts to query the PTMs through some …
as a service. It allows users to design task-specific prompts to query the PTMs through some …
[PDF][PDF] Energy balance for analysis of complex metabolic networks
Predicting behavior of large-scale biochemical networks represents one of the greatest
challenges of bioinformatics and computational biology. Computational tools for predicting fluxes …
challenges of bioinformatics and computational biology. Computational tools for predicting fluxes …